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Biotechnologically relevant features of gluconic acid production by acetic acid bacteria

Isidoro García-García, Ana M. Cañete-Rodríguez, Inés M. Santos-Dueñas, Jorge E. Jiménez-Hornero, Armin Ehrenreich, Wolfgang Liebl, Teresa García-Martínez, Juan C. Mauricio
  • Ana M. Cañete-Rodríguez
    Department of Inorganic Chemistry and Chemical Engineering, Marie Curie Building, Campus of Rabanales, University of Cordoba, Spain
  • Inés M. Santos-Dueñas
    Department of Inorganic Chemistry and Chemical Engineering, Marie Curie Building, Campus of Rabanales, University of Cordoba, Spain
  • Jorge E. Jiménez-Hornero
    Department of Computing and Numerical Analysis, Leonardo da Vinci Building, Campus of Rabanales, University of Cordoba, Spain
  • Armin Ehrenreich
    Department of Microbiology, Technical University of Munich, Freising Weihenstephan, Germany
  • Wolfgang Liebl
    Department of Microbiology, Technical University of Munich, Freising Weihenstephan, Germany
  • Teresa García-Martínez
    Department of Microbiology, Severo Ochoa Building, Campus of Rabanales, University of Cordoba, Spain
  • Juan C. Mauricio
    Department of Microbiology, Severo Ochoa Building, Campus of Rabanales, University of Cordoba, Spain

Abstract

The many uses of gluconic acid and some of its salts are arousing increasing interest in these compounds and in their production levels. Although gluconic acid and gluconates can be obtained chemically, they are currently almost exclusively biotechnologically produced, mostly by fungus based methods. There is, however, an ongoing search for alternative microorganisms to avoid the problems of using fungi for this purpose and to improve the productivity of the process. Especially promising in this respect are acetic acid bacteria, particularly Gluconobacter strains. This paper discusses the main variables and operating conditions to be considered in optimizing gluconic acid production by Gluconobacter.

Keywords

Gluconic acid; acetic acid bacteria; Gluconobacter; optimization.

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Submitted: 2016-12-09 11:40:21
Published: 2017-02-15 17:52:03
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Copyright (c) 2017 Isidoro García-García, Ana M. Cañete-Rodríguez, Inés M. Santos-Dueñas, Jorge E. Jiménez-Hornero, Armin Ehrenreich, Wolfgang Liebl, Teresa García-Martínez, Juan C. Mauricio

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