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147 | Screening of novel metabotropic glutamate receptor 4-oriented molecules in an in vitro model of Parkinson’s disease
Cristina Giuffré1, Miriana Scordino1, Giulia Urone1, Miriam Buttacavoli1, Alessandra Montalbano2, Marilia Barreca2, Roberta Bivacqua2, Paola Barraja2, Virginia Spano’2, Giuseppa Mudo’1, Valentina Di Liberto1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostic, University of Palermo, Palermo, Italy; 2Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Palermo, Italy.DOI https://doi.org/10.4081/jbr.2026.15399
- 137 abstract views
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154 | Metabolomic reprogramming and ferroptosis protection by the indole-based compound 20 against Aβ (25–35) in SH-SY5Y cells
Mariapia Vietri1, Enza Napolitano1, Carmen Marino1, Tania Ciaglia1, Rodolfo Maria Abbate1, Pietro Campiglia1, Alessia Bertamino1, Michele Manfra2, Anna Maria D’Ursi1, Ornella Moltedo1, Vincenzo Vestuto1 | 1Department of Pharmacy, University of Salerno, Fisciano, Salerno, Italy; 2Department of Health Science, University of Basilicata, Potenza, Italy.DOI https://doi.org/10.4081/jbr.2026.15406
- 178 abstract views
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148 | Lysosomal and synuclein pathology in IPSC-derived dopaminergic neurons from GBA1-mutant Parkinson’s disease patients
Gaia Pinna1, Giuseppe Uras1|2, Veronica Lentini1, Luca Miuzzo1, Sara Del Pozo3, Federico Fierli3, Anthony Schapira3, Antonella Pantaleo1 | 1Department of Biomedical Science, University of Sassari, Italy; 2Department of Haematology, UCL, London, United Kingdom; 3Department of Clinical and Movement Neurosciences, UCL, London, UK.DOI https://doi.org/10.4081/jbr.2026.15400
- 167 abstract views
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142 | Drug repositioning reveals novel therapeutic candidates for spinal muscular atrophy
Marina Boido1, Daniela Maria Rasà1, Serena Stanga1, Ersilia Nicorvo1, Pamela Santonicola2, Nadia Mazzarella3, Antonella Camera2, Roberto Iacomino2, Ilenia Matino2, Silvia Chasseur1, Giuseppina Zampi2, Piera Smeriglio4, Elia Di Schiavi2, Alessandro Vercelli1 | 1Neuroscience Institute Cavalieri Ottolenghi, Department of Neuroscience "Rita Levi Montalcini", University of Turin, Turin, Italy; 2Institute of Biosciences and BioResources IBBR, National Research Council CNR, Naples, Italy; 3Institute of Genetics and Biophysics "Adriano Buzzati-Traverso" IGB-ABT, National Research Council CNR, Naples, Italy; 4Sorbonne Université, INSERM, Institut de Myologie, Centre de Recherche en Myologie, Paris, France.DOI https://doi.org/10.4081/jbr.2026.15394
- 147 abstract views
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155 | Mitochondrial dynamics and therapeutic insights in spinal muscular atrophy: effects of MFN2 boosting in motoneurons and human fibroblasts
Francesco Paolo Zummo1, Serena Stanga1, Letizia Paladino2, Maria Beltran3, Francesco Fedeli4, Maria Rosa Soler3, Fabio Bucchieri5, Marina Boido1 | 1Department of Neuroscience “Rita Levi Montalcini”, Neuroscience Institute Cavalieri Ottolenghi, University of Turin, Italy; 2E-Campus University, Palermo, Italy; 3Neuronal Signaling Unit, Experimental Medicine Department, University of Lleida-IRBLleida, Lleida, Spain; 4University of Pavia, Italy; 5Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Italy.DOI https://doi.org/10.4081/jbr.2026.15407
- 134 abstract views
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149 | Behavioral markers of epileptogenesis and pharmacoresistance in a longitudinal pilocarpine model of temporal lobe epilepsy
Nicolò Ricciardi1, Miriana Scordino1, Giulia Urone1, Miriam Buttacavoli1, Giuseppa Mudò1, Pierangelo Sardo1, Giuseppe Giglia1|2, Valentina Di Liberto1, Giuditta Gambino1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Italy; 2Euro Mediterranean Institute of Science and Technology - IEMEST, Palermo, Italy.DOI https://doi.org/10.4081/jbr.2026.15401
- 157 abstract views
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143 | Anodal tDCS enhances decision precision during biological motion perception: a computational active inference perspective
Antonio Cangelosi1, Umberto Quartetti1, Giulio Musotto2, Dimitri Ognibene3, Giuditta Gambino1, Giuseppe Giglia1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics BiND, Section of Human Physiology, University of Palermo, Italy; 2Bioengineering Unit, RiMED Foundation, Palermo, Italy; 3Department of Psychology, University of Milan-Bicocca, Milan, Italy.DOI https://doi.org/10.4081/jbr.2026.15395
- 205 abstract views
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150 | New strategies to counteract dopaminergic degeneration: in vitro and in vivo neurotrophic properties of a tetrahydro-isoquinoline derivative as a novel mGlu2/3 agonist/positive allosteric modulator
Miriana Scordino1, Giulia Urone1, Monica Frinchi1, Lucia Seidita1, Alessandra Montalbano2, Marilia Barreca2, Paola Barraja2, Maria Valeria Raimondi2, Roberta Bivacqua2, Fanny Malhaire3, Cyril Goudet3, Giuseppa Mudò1, Virginia Spanò2, Valentina Di Liberto1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Italy; 2Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 3IGF, Université de Montpellier, CNRS, INSERM, France.DOI https://doi.org/10.4081/jbr.2026.15402
- 163 abstract views
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144 | Effect of groove music on pain perception: evidence from a behavioural and electrophysiological study
Fabrizio Di Giovanni1, Marzia Magnanini1, Antonio Cangelosi1, Giuditta Gambino1, Filippo Brighina1, Pierangelo Sardo1, Giuseppe Giglia1|2 | 1Università degli Studi di Palermo, Department of Biomedicine, Neuroscience and Advanced Diagnostics BiND, Palermo, Italy; 2Euro-Mediterranean Institute of Science and Technology IEMEST, Palermo, Italy.DOI https://doi.org/10.4081/jbr.2026.15396
- 177 abstract views
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151 | Dysregulation of the lung-brain axis induced by CMIT/MIT: oxidative stress and junctional protein impairment lead to α-synuclein accumulation and dopaminergic neurotoxicity
Nicla Tranchida1, Rosanna Di Paola2, Marika Cordaro3 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2Department of Veterinary Sciences, University of Messina, Italy; 3Department of Biomedical, Dental and Morphological and Functional Imaging University of Messina, Italy.DOI https://doi.org/10.4081/jbr.2026.15403
- 179 abstract views
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145 | Synergistic effects of APP and Tau on neuronal miRNA regulation
Laura M. De Plano1, Alessandra Saitta1, Antonella Caccamo1, Emanuele L. Sciuto1, Sabrina Conoci2, Salvatore Oddo1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2Dipartimento di Chimica "Giacomo Ciamician", University of Bologna, Italy.DOI https://doi.org/10.4081/jbr.2026.15397
- 134 abstract views
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152 | Genetic and morphological factors in cortical folding: studies on the rolandic fissure
Sophie Martinet, Fabrizio Pizzagalli, Alessandro Vercelli | Department of Neuroscience “Rita Levi Montalcini”, Neuroscience Institute Cavalieri Ottolenghi, University of Turin, Italy.DOI https://doi.org/10.4081/jbr.2026.15404
- 150 abstract views
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146 | Preventive effect of intranasal lemon-derived nanovesicles in a high-fat diet rat model of metabolic syndrome: modulation of anxiety-like behavior and survival signalling pathways
Andrea Giubilato1, Nicolò Ricciardi1, Valentina Di Liberto1, Miriana Scordino1, Giulia Urone1, Danila Di Majo1, Giuseppe Giglia1|4, Pierangelo Sardo1, Giuseppe Ferraro1, Riccardo Alessandro1|2|3, Stefania Raimondo1|2, Giuditta Gambino1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics BiND, University of Palermo, Section of Human Physiology, Biology and Genetics, Palermo, Italy; 2Navhetec srl, Spinoff of the University of Palermo, Palermo, Italy; 3Institute for Biomedical Research and Innovation IRIB, National Research Council CNR, Palermo, Italy; 4Euro Mediterranean Institute of Science and Technology-IEMEST, Palermo, Italy.DOI https://doi.org/10.4081/jbr.2026.15398
- 208 abstract views
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153 | α-synuclein regulation in brain and bone marrow is releted to the differential expression of GATA1 transcription factor
Viola Velardi1, Francesca Arciprete1, Claudia Caturano,1Rosa Alba Rana1, Romina Mancinelli2, Maria Zingariello1, Giorgio Vivacqua1 | 1Unit of Microscopic and Ultrastructural Anatomy, University Campus Bio-Medico, Rome, Italy; 2Department of Anatomic, Histologic, Forensic Medicine and Locomotor Apparatus Science, Sapienza University of Rome, Italy.DOI https://doi.org/10.4081/jbr.2026.15405
- 144 abstract views
Session VIII - Neuroscience
14 articles