https://doi.org/10.4081/jbr.2023.11027
Immuno-oncological treatment of non-small-cell lung cancer in advanced stage with nivolumab
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Published: 2 March 2023
The field of immuno-oncology has brought about a significant paradigm shift in the therapeutic approach to cancer. The implementation of a novel therapeutic approach that seeks to stimulate the immune system's response to malignant cells has resulted in a notable alteration in the clinical trajectory of advanced Non-Small Cell Lung Cancer (NSCLC) treatment. The objective of our study was to assess the therapeutic effectiveness of nivolumab as a standalone treatment for patients diagnosed with advanced stage IIIB/IV non-small cell lung cancer, namely those who had progressed beyond the second line of treatment. The findings demonstrated a progression-free survival duration of 7.35 months and a notable enhancement in patients' quality of life when compared to alternative therapeutic interventions. Furthermore, it was shown that patients who received Nivolumab did not experience any adverse reactions classified as type 3 or type 4. It is anticipated that the encouraging findings obtained thus far will contribute to a future enhancement in overall survival rates.
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