A CROSS-SECTIONAL STUDY OF WORKERS WITH OCCUPATIONAL EXPOSURE TO PETROLEUM DERIVATIVES


Published: October 31, 2000
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Human involucrin (hiNV) is an early cytoplasmatic protein of the cornified cell envelope (1, 2) that is considered as a marker of normal keratinocyte differentiation and maturation (3,4). In keratinocytes the formation of the cornified cell envelope is needed to enable skin to withstand physical, mechanical and chemical agents ( 5) .

In normal orthokeratinized body, hiNV expression begins in the upper spinous layer coincident with cell flattening (6); however deeper epidermal staining for hiNV has been described in hyperproliferative and diseased epidermis ( 5) . [...]


Fenga, C., Spatari, G., Loreto, C., Leonardi, R., & Germanò, D. (2000). A CROSS-SECTIONAL STUDY OF WORKERS WITH OCCUPATIONAL EXPOSURE TO PETROLEUM DERIVATIVES. Journal of Biological Research - Bollettino Della Società Italiana Di Biologia Sperimentale, 76(9-10). https://doi.org/10.4081/jbr.2000.10797

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