Taopatch® combined with home-based training protocol to prevent sedentary lifestyle and biochemical changes in MS patients during COVID-19 pandemic


Submitted: 25 May 2021
Accepted: 4 August 2021
Published: 31 August 2021
Abstract Views: 2984
PDF: 771
HTML: 73
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

  • Alessandra Amato Department of Psychological, Pedagogical and Educational Sciences, Sport and Exercise Sciences Research Unit, University of Palermo, Italy.
  • Giuseppe Messina Department of Psychological, Pedagogical and Educational Sciences, Sport and Exercise Sciences Research Unit, University of Palermo, Italy.
  • Kaltrina Feka Department of Psychological, Pedagogical and Educational Sciences, Sport and Exercise Sciences Research Unit, University of Palermo, Italy.
  • Diego Genua Department of Psychological, Pedagogical and Educational Sciences, Sport and Exercise Sciences Research Unit, University of Palermo, Italy.
  • Paolo Ragonese Department of Biomedicine, Neurosciences and Advanced Diagnostics (Dipartimento di Biomedicina, Neuroscienze e Diagnostica avanzata) (Bi.N.D.), University of Palermo, Italy.
  • Dorota Kostrzewa-Nowak Faculty of Physical Education and Health Promotion, University of Szczecin, Szczecin, Poland; Institute of Physical Culture Sciences, University of Szczecin, Szczecin, Poland.
  • Francesco Fischetti Department of Basic Medical Sciences, Neuroscience and Sense Organs, School of Medicine, University of Study of Bari, Italy.
  • Angelo Iovane Department of Psychological, Pedagogical and Educational Sciences, Sport and Exercise Sciences Research Unit, University of Palermo, Italy.
  • Patrizia Proia Department of Psychological, Pedagogical and Educational Sciences, Sport and Exercise Sciences Research Unit, University of Palermo, Italy.

In Multiple sclerosis (MS) it is important to preserve the residual physiological functions of subjects. The aim of the present study was to investigate the influence of nanotechnological device treatment combined with home-based training program (TP) on lactate level, hand grip strength and cervical mobility on MS patients. Seventeen MS patients were enrolled in the study and randomly assigned to an experimental group (EG) in which the Taopatch® nanotechnological device was applied or to a control group (CG). All the participants carried out a cervical range of motion (1) assessment and the hand grip test at baseline (T0) and after TP (T1), also investigating the lactate levels to figure out if there could be a correlation with the possible changes in the investigated parameters. The results showed no significant differences in both groups for ROM. As regards the hand grip test, EG showed a statistically significant improvement on strength for both hands, dominant (p = 0.01) and non-dominant (p = 0.04), while the CG showed an improvement only for the non-dominant hand (p = 0.001). No correlation was found between baseline lactate level and cervical ROM change. We can definitely conclude that exercise and Taopatch® can help to improve and maintain hand strength in MS subjects and also can prevent sedentary lifestyle during the COVID-19 pandemic time. These are preliminary results that need further investigations, possibly increasing sample size and lengthening time of intervention.


Dobson R, Giovannoni G. Multiple sclerosis - a review. Eur J Neurol. 2019 Jan;26(1):27-40. Epub 2018 Nov 18. DOI: https://doi.org/10.1111/ene.13819

Karussis D. The diagnosis of multiple sclerosis and the various related demyelinating syndromes: a critical review. J Autoimmun. 2014 Feb-Mar;48-49:134-42. Epub 2014 Feb 10. DOI: https://doi.org/10.1016/j.jaut.2014.01.022

Owens B. Multiple sclerosis. Nature. 2016 Nov 30;540(7631):S1. DOI: https://doi.org/10.1038/540S1a

Gross HJ, Watson C. Characteristics, burden of illness, and physical functioning of patients with relapsing-remitting and secondary progressive multiple sclerosis: a cross-sectional US survey. Neuropsychiatr Dis Treat. 2017 May 18;13:1349-1357. DOI: https://doi.org/10.2147/NDT.S132079

Proia P, Amato A, Puleo R, Arnetta F, Rizzo F, Di Grigoli L, Zangla D, Schirò G, Ragonese P, Messina G. Efficacy of 12 Weeks of Proprioceptive Training in Patients with Multiple Sclerosis. Journal of Human Sport and Exercise. 2019; 14 (5proc): S1986-S1992. DOI: https://doi.org/10.14198/jhse.2019.14.Proc5.19

Kalichman L, Ben David C. Effect of self-myofascial release on myofascial pain, muscle flexibility, and strength: A narrative review. J Bodyw Mov Ther. 2017 Apr;21(2):446-451. Epub 2016 Nov 14. DOI: https://doi.org/10.1016/j.jbmt.2016.11.006

Amato A, Messina G, Giustino V, Brusa J, Brighina F, Proia P. A pilot study on non-invasive treatment of migraine: The self-myofascial release. Eur J Transl Myol. 2021 Mar 26;31(1):9646.

Amorini AM, Nociti V, Petzold A, Gasperini C, Quartuccio E, Lazzarino G, Di Pietro V, Belli A, Signoretti S, Vagnozzi R, Lazzarino G, Tavazzi B. Serum lactate as a novel potential biomarker in multiple sclerosis. Biochim Biophys Acta. 2014 Jul;1842(7):1137-43. Epub 2014 Apr 13. DOI: https://doi.org/10.1016/j.bbadis.2014.04.005

Lomeo A, Cacciaguerra G, Garsia D, Scolaro A. Utilisation des dispositifs nanotechnologiques dans les pathologies dégénératives cérébrales. Étude prospective sur 28 patients atteints de sclérose en plaques. Hegel. 2019:2:114. DOI: https://doi.org/10.4267/2042/70215

Battaglia G. Influence of Occlusal Vertical Dimension on Cervical Spine Mobility in Sports Subjects. Acta Medica Mediterr. 2016; doi:10.19193/0393-6384_2016_5_135.

Battaglia G, Messina G, Giustino V, Zangla D, Barcellona M, Iovane A, Palma A. Influence of Vertical Dimension of Occlusion on Peak Force During Handgrip Tests in Athletes. Asian J Sports Med. 2018, In Press, doi:10.5812/asjsm.68274. DOI: https://doi.org/10.5812/asjsm.68274

Burke JR, Papuga MO. Effects of foot orthotics on running economy: methodological considerations. J Manipulative Physiol Ther. 2012 May;35(4):327-36. DOI: https://doi.org/10.1016/j.jmpt.2012.04.001

Carbonari B, Balducci F, Cesaretti G, Cesanelli L, Botticelli D, Messina G. Performance, balance and posture variations with Occlusal Splint and Taopatch® devices: a retrospettive cross-over study. J Sports Med Phys Fitness. 2021 Feb;61(2):317-323. Epub 2020 Jul 30. DOI: https://doi.org/10.23736/S0022-4707.20.11053-3

Cataldi S, Francavilla VC, Bonavolontà V, De Florio O, Carvutto R, De Candia M, Latino F, Fischetti F. Proposal for a Fitness Program in the School Setting during the COVID 19 Pandemic: Effects of an 8-Week CrossFit Program on Psychophysical Well-Being in Healthy Adolescents. Int J Environ Res Public Health. 2021 Mar 18;18(6):3141. DOI: https://doi.org/10.3390/ijerph18063141

Hebisz P, Hebisz R, Murawska-Ciałowicz E, Zatoń M. Changes in exercise capacity and serum BDNF following long-term sprint interval training in well-trained cyclists. Appl Physiol Nutr Metab. 2019 May;44(5):499-506. Epub 2018 Oct 4. DOI: https://doi.org/10.1139/apnm-2018-0427

Kim M, Lee M, Kim M, Oh S, Jung S, Yoon B. Effectiveness of therapeutic inflatable ball self-exercises for improving shoulder function and quality of life in breast cancer survivors after sentinel lymph node dissection. Support Care Cancer. 2019 Jul;27(7):2349-2360. Epub 2019 Mar 12. DOI: https://doi.org/10.1007/s00520-019-4656-0

L Liu K, Zhou Y, Xie W, Gu Z, Jin Y, Ye X, Chen X, Fan B, Wang H, Cui Y. Handgrip exercise reduces peripherally-inserted central catheter-related venous thrombosis in patients with solid cancers: A randomized controlled trial. Int J Nurs Stud. 2018 Oct;86:99-106. Epub 2018 Jun 22. DOI: https://doi.org/10.1016/j.ijnurstu.2018.06.004

Amato A, Messina G, Giustino V, Brusa J, Brighina F, Proia P. A pilot study on non-invasive treatment of migraine: The self-myofascial release. Eur J Transl Myol. 2021 Mar 26;31(1):9646. PMID: 33709650; PMCID: PMC8056163. DOI: https://doi.org/10.4081/ejtm.2020.9646

Fritz NE, Newsome SD, Eloyan A, Marasigan RE, Calabresi PA, Zackowski KM. Longitudinal relationships among posturography and gait measures in multiple sclerosis. Neurology. 2015 May 19;84(20):2048-56. Epub 2015 Apr 15. DOI: https://doi.org/10.1212/WNL.0000000000001580

Malchiodi Albedi G, Corna S, Aspesi V, Clerici D, Parisio C, Seitanidis J, Cau N, Brugliera L, Capodaglio P. Effects of nanotechnology-based devices on postural control in healthy subjects. J Sports Med Phys Fitness. 2018 Oct;58(10):1418-1422. Epub 2017 Sep 5. DOI: https://doi.org/10.23736/S0022-4707.17.07530-2

Chen G, Ågren H, Ohulchanskyy TY, Prasad PN. Light upconverting core-shell nanostructures: nanophotonic control for emerging applications. Chem Soc Rev. 2015 Mar 21;44(6):1680-713. DOI: https://doi.org/10.1039/C4CS00170B

Lamers I, Kerkhofs L, Raats J, Kos D, Van Wijmeersch B, Feys P. Perceived and actual arm performance in multiple sclerosis: relationship with clinical tests according to hand dominance. Mult Scler. 2013 Sep;19(10):1341-8. Epub 2013 Feb 13. DOI: https://doi.org/10.1177/1352458513475832

Gordon NM, Rudroff T, Enoka JA, Enoka RM. Handedness but not dominance influences variability in endurance time for sustained, submaximal contractions. J Neurophysiol. 2012 Sep;108(5):1501-10. Epub 2012 Jun 13. DOI: https://doi.org/10.1152/jn.01144.2011

Severijns D, Lamers I, Kerkhofs L, Feys P. Hand grip fatigability in persons with multiple sclerosis according to hand dominance and disease progression. J Rehabil Med. 2015 Feb;47(2):154-60. DOI: https://doi.org/10.2340/16501977-1897

Schwid SR, Goodman AD, McDermott MP, Bever CF, Cook SD. Quantitative functional measures in MS: what is a reliable change? Neurology. 2002 Apr 23;58(8):1294-6. DOI: https://doi.org/10.1212/WNL.58.8.1294

Iyengar V, Santos MJ, Ko M, Aruin AS. Grip force control in individuals with multiple sclerosis. Neurorehabil Neural Repair. 2009 Oct;23(8):855-61. Epub 2009 Jun 16. DOI: https://doi.org/10.1177/1545968309338194

Messina G, Amato A, Brighina F, Lo Monaco A, Giustino V, Brusa J, Iovane A, Proia P. Lactate Level and Handgrip Test in Migraine and Fibromyalgia after Self-Myofascial Release Treatment. Journal of Human Sport and Exercise. 2019 14(5proc), S2019-S2025. DOI: https://doi.org/10.14198/jhse.2019.14.Proc5.23

Newsome SD, von Geldern G, Shou H, Baynes M, Marasigan RER, Calabresi PA, Zackowski KM. Longitudinal assessment of hand function in individuals with multiple sclerosis. Mult Scler Relat Disord. 2019 Jul;32:107-113. Epub 2019 May 6. DOI: https://doi.org/10.1016/j.msard.2019.04.035

Barrett LE, Cano SJ, Zajicek JP, Hobart JC. Can the ABILHAND handle manual ability in MS? Mult Scler. 2013 May;19(6):806-15. Epub 2012 Oct 24. DOI: https://doi.org/10.1177/1352458512462919

Amato, A., Messina, G. ., Feka, K., Genua, D., Ragonese, P., Kostrzewa-Nowak , D., Fischetti, F., Iovane, A., & Proia, P. (2021). Taopatch® combined with home-based training protocol to prevent sedentary lifestyle and biochemical changes in MS patients during COVID-19 pandemic. European Journal of Translational Myology, 31(3). https://doi.org/10.4081/ejtm.2021.9877

Downloads

Download data is not yet available.

Citations