Prospects of plasmapheresis for patients with severe COVID-19


Submitted: 5 June 2020
Accepted: 2 September 2020
Published: 9 September 2020
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Authors

  • Ilmira R. Gilmutdinova Federal State Budgetary Institution “National Medical Research Centre for Rehabilitation and Balneology” of the Ministry of Health of Russia, Moscow, Russian Federation.
  • Maksim Yu. Yakovlev Federal State Budgetary Institution “National Medical Research Centre for Rehabilitation and Balneology” of the Ministry of Health of Russia, Moscow, Russian Federation.
  • Petr S. Eremin Federal State Budgetary Institution “National Medical Research Centre for Rehabilitation and Balneology” of the Ministry of Health of Russia, Moscow, Russian Federation.
  • Anatoliy D. Fesun Federal State Budgetary Institution “National Medical Research Centre for Rehabilitation and Balneology” of the Ministry of Health of Russia, Moscow, Russian Federation.

On February 11, 2020, the World Health Organization officially named the infection caused by the new coronavirus “Coronavirus disease 2019” (COVID-19). On February 11, 2020, the International Committee on Taxonomy of Viruses (ICTV) officially named the infectious matter “severe acute respiratory syndrome coronavirus 2” (SARS-CoV-2). Emergence of severe complications with new coronavirus disease is due to the development of hypercytokinaemia, also known as “cytokine storm”. These complications comprise acute respiratory distress syndrome (ARDS), respiratory failure and death. Emerging data point to the logic of using extracorporeal haemocorrection to normalise cytokine levels and reduce the severity of organ disorders. The analysis of the literature indicates that to date, a certain positive experience has been accumulated in the world in the application of extracorporeal methods in clinical practice in patients with COVID-19.


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