Relevance of lactate level detection in migrane and fibromyalgia


Submitted: 5 April 2019
Accepted: 17 April 2019
Published: 9 May 2019
Abstract Views: 1743
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Authors

  • Patrizia Proia Department of Psychology, Educational Science and Human Movement, University of Palermo, Italy.
  • Alessandra Amato Department of Psychology, Educational Science and Human Movement, University of Palermo, Italy.
  • Valentina Contrò Department of Psychology, Educational Science and Human Movement, University of Palermo, Italy.
  • Alessandra Lo Monaco Department of Psychology, Educational Science and Human Movement, University of Palermo, Italy.
  • Jessica Brusa Department of Psychology, Educational Science and Human Movement, University of Palermo, Italy.
  • Filippo Brighina Department of Experimental Biomedicine and Clinical Neurosciences (BIONEC), University of Palermo, Italy.
  • Giuseppe Messina Department of Psychology, Educational Science and Human Movement, University of Palermo, Italy.

The aim of this study was to determine the blood lactate levels in healthy and pathological subjects, particularly with migraine and fibromyalgia. Moreover we investigated the possible correlation between lactate concentration, postural stability and balance disorders; the composition of the groups were: migraine (n = 25; age 49.7 ± 12.5), fibromyalgia (n = 10; age 43.7 ± 21.2), control group (n = 16 age 28.52 ± 2.4). The results showed that patients with fibromyalgia (FG) had higher lactate levels compared to migraine (MG) and control group (CG) (mean ± sd: FG = 1.78 ± 0.9 mmol/L; MG = 1.45±1 mmol/L; CG = 0,85 ± 0,07 mmol/L). The same situation was highlighted about the sway path length with eyes closed (FG = 518 ± 195 mm; MG = 465 ± 165 mm; CG = 405 ± 94,72 mm) and with eyes open (FG = 430 ± 220 mm; MG = 411 ± 143 mm; CG = 389 ± 107 mm). This can be explained by the fact that energy-intensive postural strategies must be used to optimize both static and dynamic coordination, in particular with repeated contractions of tonic oxidative muscle cells responsible for postural control.


Proia, P., Amato, A., Contrò, V., Lo Monaco, A., Brusa, J., Brighina, F., & Messina, G. (2019). Relevance of lactate level detection in migrane and fibromyalgia. European Journal of Translational Myology, 29(2). https://doi.org/10.4081/ejtm.2019.8202

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