The effect of Dayak onion brewed water in reducing blood pressure and mean arterial pressure (MAP) in hypertensive patients


Submitted: 12 September 2023
Accepted: 6 November 2023
Published: 21 November 2023
Abstract Views: 400
PDF: 142
HTML: 7
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

Background: The World Health Organization (WHO) estimated that 1.28 billion adults aged 30-79 years worldwide suffered from hypertension. Dayak onion is an herbal plant found in Indonesia, particularly in Kalimantan and traditionally used to treat hypertension. The purpose of this study was to determine the effect of Dayak onion steeping water on the reduction of systolic-diastolic blood pressure and mean arterial pressure (MAP) in hypertensive patients.

Methods: This study employed a quasi-experimental research design with a time series approach, utilizing a pre-post-test design with a control group. The sample included two groups (intervention and control), totaling 30 participants. The independent variable was the steeping of Dayak onion bulbs, while the dependent variables were blood pressure values and MAP. The instruments used were Standard Operating Procedures (SPO) Dayak onion herb, SPO blood pressure measurement, SPO calculation of MAP, and a digital sphygmomanometer. Data analysis was performed using paired t-tests.

Results: The results of the paired t-test statistical analysis of systolic-diastolic values and MAP in each group revealed significant findings. In the intervention group, a significant result was obtained in the pre-post test difference test, with a p-value of < 0.05 from day 1 to day 3 assessments. This suggests that Dayak onion steeping water had an effect on systolic-diastolic and MAP values in the intervention group. In contrast, the pre-post test in the control group yielded a p-value of < 0.05 for systolic values on days 2 and 3, diastolic values on days 1 and 3, and MAP values on days 1, 2, and 3. This indicates differences in systolic-diastolic and MAP values in the pre-post assessments, although these differences were not evenly distributed across every day.

Conclusion: The study found that Dayak onion steeping water had an effect on systolic-diastolic and MAP values in the intervention group. Thus, the use of Dayak onion steeping water, containing allicin, can be considered an approach for controlling hypertension in the realm of complementary and alternative medicine, utilizing natural ingredients for herbal therapy.


Israfil I, Kusnanto K, Yusuf A, Efendi F. The effect of health education intervention through mobile phone on hypertension patients: A systematic review. Med J Malaysia 2022;77:232–6.

Kalish LA, Buczynski B, Connell P, et al. Stop Hypertension with the Acupuncture Research Program (SHARP): Clinical trial design and screening results. Control Clin Trials 2004;25:76–103. DOI: https://doi.org/10.1016/j.cct.2003.08.006

Makhfudli, Susanto J, Sairozi A, Ubudiyah M. Determinants of Hypertension in Outpatients in East Java, Indonesia. J Pak Med Assoc 2023;73:S113–7. DOI: https://doi.org/10.47391/JPMA.Ind-S2-27

Escobar E. Hypertension and coronary heart disease. J Hum Hypertens 2002;16:S61–3. DOI: https://doi.org/10.1038/sj.jhh.1001345

WHO. Hypertension. WHO. 2023 Available from: https://www.who.int/news-room/fact-sheets/detail/hypertension

Kusumaningrum T, Pratiwi IN, Wahyu N, et al. Factors associated with hypertension in women of childbearing age. The 13th International Nursing Conference 2021;73:109–12. DOI: https://doi.org/10.47391/JPMA.Ind-S2-26

Kementerian Kesehatan RI Badan Penelitian dan Pengembangan Kesehatan. Hasil Utama RISKESDAS 2018. https://kesmas.kemkes.go.id/assets/upload/dir_519d41d8cd98f00/files/Hasil-riskesdas-2018_1274.pdf. 2018.

WHO. Hypertension. 2023 [cited 2023 Oct 30]. Available from: https://www.who.int/news-room/fact-sheets/detail/hypertension

Carey RM, Moran AE, Whelton PK. Treatment of Hypertension: A Review. JAMA 2022;328:1849–61. DOI: https://doi.org/10.1001/jama.2022.19590

Purnawan IN, Widati S, Wahyuni CU. A cross-sectional study: a hypertension screening model using digital tensimeter as the gold standard at public health centre in GianyarRegency, Bali Province, Indonesia. J Public Health Afr 2023;14:1–5. DOI: https://doi.org/10.4081/jphia.2023.2550

Pristianty L, Priyandani Y, Rahem A. The correlation between knowledge, attitude and family support on compliance of outpatients with hypertension in a healthcare centre in Indonesia. Pharm Educ 2023;23:25–30. DOI: https://doi.org/10.46542/pe.2023.232.2530

Wijaya IN, Athiyah U, Fasich, et al. The association between drug therapy problems and blood pressure control of patients with hypertension in public health center setting. J Public Health Afr 2023;14:137–40. DOI: https://doi.org/10.4081/jphia.2023.2531

Ali-Shtayeh MS, Jamous RM, Jamous RM, Salameh NMY. Complementary and alternative medicine (CAM) use among hypertensive patients in Palestine. Complement Ther Clin Pract 2013;19:256–63. DOI: https://doi.org/10.1016/j.ctcp.2013.09.001

Afik A, Fikriana R. Self-care Experience in Hypertensive Patients. Bali Med J 2021;10:1398–402. DOI: https://doi.org/10.15562/bmj.v10i3.2982

Pristianty L, Hingis ES, Priyandani Y, Rahem A. Relationship between knowledge and adherence to hypertension treatment. J Public Health Afr 2023;14:2502. DOI: https://doi.org/10.4081/jphia.2023.2502

Ng JY, Gilotra K. Complementary medicine mention and recommendations are limited across hypertension guidelines: A systematic review. Complement Ther Med 2020;50:102374. DOI: https://doi.org/10.1016/j.ctim.2020.102374

Hass DJ. Complementary and Alternative Medicine. In: Sleisenger and Fordtran’s Gastrointestinal and Liver Disease. Elsevier; 2010. P. 2287-2299.e3. DOI: https://doi.org/10.1016/B978-1-4160-6189-2.00127-X

Dada R, Sabharwal P, Sharma A, Henkel R. Use of herbal medicine as primary or supplementary treatments. In: Herbal Medicine in Andrology. Elsevier; 2021. P. 9–15. DOI: https://doi.org/10.1016/B978-0-12-815565-3.00002-3

Kamarudin AA, Sayuti NH, Saad N, Razak NAAb, Esa Nmohd. Eleutherine bulbosa (Mill.) Urb. Bulb: Review of the Pharmacological Activities and Its Prospects for Application. Int J Mol Sci 2021;22:6747. DOI: https://doi.org/10.3390/ijms22136747

Prayitno B, Mukti BH, Lagiono. Optimasi Potensi Bawang Dayak (Eleutherine Sp.) Sebagai Bahan Obat Alternatif. Jurnal Pendidikan Hayati 2018;3:149–58.

Swandari Paramita, Muhammad Khairul Nuryanto. Anti-inflammatory activity of bawang ayak (eleutherine bulbosa (mill. Urb.))Ethanol bulb extracts. J Vocat Health Stud 2018;51–5. DOI: https://doi.org/10.20473/jvhs.V2.I2.2018.51-55

Chan JYY, Yuen ACY, Chan RYK, Chan SW. A Review of the Cardiovascular Benefits and Antioxidant Properties of Allicin. Phytother Res 2013;27:637–46. DOI: https://doi.org/10.1002/ptr.4796

Utami P, Mardiana L, Penulis PS T. Umbi Ajaib: Tumpas Penyakit. Nugroho S, Kusumaningtiyas P, W. B, P, editors. Jakarta: Penerbar Swadaya; 2013.

Lidiková J, Čeryová N, Tóth T, et al. Garlic (Allium sativum L.): Characterization of Bioactive Compounds and Related Health Benefits. In: Herbs and Spices – New Advances. IntechOpen; 2023. DOI: https://doi.org/10.5772/intechopen.108844

Handayani S, Dewantari EM, My C, Fitria N, Kesehatan FI. Pengaruh Pemberian The Bawang Dayak Terhadap Penurunan Tekanan Darah Pada Penderita Hipertensi. Jurnal Perawat Indonesia 2021;5:724–30.

Tetty Junita Purba. Pengaruh Pemberian The Bawang Dayak Terhadap Penurunan Hipertensi Pada Lansia. BEST J 2021;5:393–8.

Salehi B, Zucca P, Orhan IE, et al. Allicin and health: A comprehensive review. Trends Food Sci Technol 2019;86:502–16. DOI: https://doi.org/10.1016/j.tifs.2019.03.003

García-Trejo EMA, Arellano-Buendía AS, Argüello-García R, et al. Effects of Allicin on Hypertension and Cardiac Function in Chronic Kidney Disease. Oxid Med Cell Longev 2016;2016:1–13. DOI: https://doi.org/10.1155/2016/3850402

Bhardwaj K, Verma M, Verma N, et al. Effect of long term supplementation of active garlic allicin in reducing blood pressure in hypertensive subjects. Int J Adv Med 2015;231–4. DOI: https://doi.org/10.18203/2349-3933.ijam20150550

Chan JYY, Tsui HT, Chung IYM, et al. Allicin protects rat cardiomyoblasts (H9c2 cells) from hydrogen peroxide-induced oxidative injury through inhibiting the generation of intracellular reactive oxygen species. Int J Food Sci Nutr 2014;65:868–73. DOI: https://doi.org/10.3109/09637486.2014.925428

Cui T, Liu W, Chen S, et al. Antihypertensive effects of allicin on spontaneously hypertensive rats via vasorelaxation and hydrogen sulfide mechanisms. Biomed Pharmacother 2020;128:110240. DOI: https://doi.org/10.1016/j.biopha.2020.110240

Putri AY, Pikir BS, Oktaviono YH, Alzahra F. Effects of Garlic Extract (allicin) on Proliferation of Endothelial Progenitor Cells (EPC) in Patients with Stable Coronary Artery Disease. In: IOP Conference Series: Earth and Environmental Science. 2020. DOI: https://doi.org/10.1088/1755-1315/441/1/012163

Shang A, Cao SY, Xu XY, et al. Bioactive Compounds and Biological Functions of Garlic (Allium sativum L.). Foods 2019;8:246. DOI: https://doi.org/10.3390/foods8070246

Setiani, D., Shoufiah, R., Widiastuti, H. P., Imamah, I. N., Firdaus, R., & Andrianur, F. (2023). The effect of <i>Dayak</i> onion brewed water in reducing blood pressure and mean arterial pressure (MAP) in hypertensive patients. Healthcare in Low-Resource Settings, 11(2). https://doi.org/10.4081/hls.2023.11776

Downloads

Download data is not yet available.

Citations