Reviews
Vol. 10 No. 1 (2022)
https://doi.org/10.4081/hls.2022.10800
COVID-19 and neurological complications: A review
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Received: 13 August 2022
Accepted: 14 November 2022
Published: 28 November 2022
Accepted: 14 November 2022
Published: 28 November 2022
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Infections with viruses have detrimental effects on neurological functions, and even cause severe neurological damage. There is mounting evidence that coronaviruses (CoV) as well as SARS-CoV-2 exhibit neurotropic abilities and might cause neurological problems. Neuroinvasive viruses are not fully understood, which makes it important to investigate their impact on the nervous system. In this paper, we review research into neurological complications associated with CoV.
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Chaplin S. COVID‐19: a brief history and treatments in development. Prescriber 2020;31:23-8. DOI: https://doi.org/10.1002/psb.1843
Zhu N, Zhang D, Wang W, et al. A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med 2020;382:727-33. DOI: https://doi.org/10.1056/NEJMoa2001017
Deng S-Q, Peng H-J. Characteristics of and Public Health Responses to the Coronavirus Disease 2019 Outbreak in China. J Clin Med 2020;9:575. DOI: https://doi.org/10.3390/jcm9020575
Hassan SA, Sheikh FN, Jamal S, et al. Coronavirus (COVID-19): A Review of Clinical Features, Diagnosis, and Treatment. Cureus 2020;12:e7355. DOI: https://doi.org/10.7759/cureus.7355
Kanwar D, Imran M, Wasay M. Neurological involvement in Coid-19 infections; pathophysiology, presentation and outcome. Pakistan J Neurol Sci 2020;15:52-8.
Carod-Artal FJ. Neurological complications of coronavirus and COVID-19. Revista de Neurologia 2020;70:311-22. DOI: https://doi.org/10.33588/rn.7009.2020179
Zhou Y, Li W, Wang D, et al. Clinical time course of COVID-19, its neurological manifestation and some thoughts on its management. Stroke Vasc Neurol 2020;5:177-179. DOI: https://doi.org/10.1136/svn-2020-000398
Ellul MA, Benjamin L, Singh B, et al. Neurological associations of COVID-19. Lancet Neurol 2020;19:767-783. DOI: https://doi.org/10.1016/S1474-4422(20)30221-0
Baker D, Amor S, Kang AS, et al. The underpinning biology relating to multiple sclerosis disease modifying treatments during the COVID-19 pandemic. Mult Scler Relat Disord 2020;43:102174. DOI: https://doi.org/10.1016/j.msard.2020.102174
Venkatesan A, Tunkel AR, Bloch KC, et al. Case definitions, diagnostic algorithms, and priorities in encephalitis: consensus statement of the international encephalitis consortium. Clin Infect Di 2013;57:1114-28. DOI: https://doi.org/10.1093/cid/cit458
Fehr AR, Perlman S. Coronaviruses: an overview of their replication and pathogenesis. Methods Mol Biol 2015;1282:1-23. DOI: https://doi.org/10.1007/978-1-4939-2438-7_1
Lima M, Siokas V, Aloizou A-M, et al. Unraveling the possible routes of SARS-COV-2 invasion into the central nervous system. Curr Treat Options Neurol 2020;22:37 DOI: https://doi.org/10.1007/s11940-020-00647-z
Dewanjee S, Vallamkondu J, Kalra RS, et al. Emerging COVID-19 Neurological Manifestations: Present Outlook and Potential Neurological Challenges in COVID-19 Pandemic. Mol Neurobiol 2021;58:4694-4715. DOI: https://doi.org/10.1007/s12035-021-02450-6
Li YC, Bai WZ, Hashikawa T. The neuroinvasive potential of SARS‐CoV2 may play a role in the respiratory failure of COVID‐19 patients. J Med Virol 2020;92:552-5. DOI: https://doi.org/10.1002/jmv.25728
Bilinska K, Jakubowska P, Von Bartheld CS, Butowt R. Expression of the SARS-CoV-2 entry proteins, ACE2 and TMPRSS2, in cells of the olfactory epithelium: identification of cell types and trends with age. ACS Chem Neurosci 2020;11:1555-62. DOI: https://doi.org/10.1021/acschemneuro.0c00210
Yavarpour-Bali H, Ghasemi-Kasman M. Update on neurological manifestations of COVID-19. Life Sci 2020;257:118063. DOI: https://doi.org/10.1016/j.lfs.2020.118063
Iadecola C, Anrather J, Kamel H. Effects of COVID-19 on the nervous system. Cell. 2020;183:16-27.e1. DOI: https://doi.org/10.1016/j.cell.2020.08.028
Lodigiani C, Iapichino G, Carenzo L, et al. Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy. Thromb Res 2020;191:9-14. DOI: https://doi.org/10.1016/j.thromres.2020.04.024
Hamming I, Timens W, Bulthuis M, et al. Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis. J Pathol 2004;203:631-7. DOI: https://doi.org/10.1002/path.1570
Abdennour L, Zeghal C, Dème M, Puybasset L, eds. Interaction cerveau-poumon. Annales francaises d'anesthesie et de reanimation; 2012: Elsevier. DOI: https://doi.org/10.1016/j.annfar.2012.04.013
Guo Y-R, Cao Q-D, Hong Z-S, et al. The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak–an update on the status. Military Med Res 2020;7:1-10. DOI: https://doi.org/10.1186/s40779-020-00240-0
Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet 2020;395:497-506. DOI: https://doi.org/10.1016/S0140-6736(20)30183-5
Wang Q, Zhang Y, Wu L, et al. Structural and functional basis of SARS-CoV-2 entry by using human ACE2. Cell 2020;181:894-904. e9. DOI: https://doi.org/10.1016/j.cell.2020.03.045
Wan S, Yi Q, Fan S, Lv J, et al. Characteristics of lymphocyte subsets and cytokines in peripheral blood of 123 hospitalized patients with 2019 novel coronavirus pneumonia (NCP). MedRxiv. 2020. DOI: https://doi.org/10.1101/2020.02.10.20021832
Sankowski R, Mader S, Valdés-Ferrer SI. Systemic inflammation and the brain: novel roles of genetic, molecular, and environmental cues as drivers of neurodegeneration. Front Cellular Neurosci 2015;9:28. DOI: https://doi.org/10.3389/fncel.2015.00028
Sasannejad C, Ely EW, Lahiri S. Long-term cognitive impairment after acute respiratory distress syndrome: a review of clinical impact and pathophysiological mechanisms. Critical Care 2019;23:1-12. DOI: https://doi.org/10.1186/s13054-019-2626-z
McNeil JB, Hughes CG, Girard T, et al. Plasma biomarkers of inflammation, coagulation, and brain injury as predictors of delirium duration in older hospitalized patients. PLoS One 2019;14:e0226412. DOI: https://doi.org/10.1371/journal.pone.0226412
Heneka MT, Carson MJ, El Khoury J, et al. Neuroinflammation in Alzheimer's disease. Lancet Neurol 2015;14:388-405. DOI: https://doi.org/10.1016/S1474-4422(15)70016-5
Pape K, Tamouza R, Leboyer M, Zipp F. Immunoneuropsychiatry—novel perspectives on brain disorders. Nature Revi Neurol 2019;15:317-28. DOI: https://doi.org/10.1038/s41582-019-0174-4
Rogers JP, Chesney E, Oliver D, et al. Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID-19 pandemic. Lancet Psychiat 2020;7:611-27. DOI: https://doi.org/10.1016/S2215-0366(20)30203-0
How to Cite
COVID-19 and neurological complications: A review. (2022). Healthcare in Low-Resource Settings, 10(1). https://doi.org/10.4081/hls.2022.10800
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