https://doi.org/10.4081/ecj.2026.14635
Early recognition and coordinated care in spinal cord infarction recovery
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Published: 26 May 2026
Spinal Cord Infarction (SCI) is a rare condition lacking standardized acute treatment guidelines. We report the case of a 23-year-old woman on estrogen-progestin therapy who presented with sudden-onset paraplegia and sensory loss below L4. Despite a normal initial spinal MRI, clinical suspicion of spinal cord ischemia led to intravenous thrombolysis within 4 hours. Aortic CT angiography excluded dissection. The patient achieved complete neurological recovery. Multidisciplinary emergency collaboration—neurology, emergency medicine, radiology, nursing, and technicians—was essential to the outcome. Follow-up MRI confirmed anterior cord lesions at D11–D12. This case underscores the value of clinical judgment, rapid team-based management, and suggests that IV thrombolysis may be a reasonable option in selected SCI cases, pending further evidence.
Downloads
1. Focke JK, Seitz RJ. Reversal of acute spinal cord ischemia by intravenous thrombolysis. Neurol Clin Pract 2021;11:e975-6. DOI: https://doi.org/10.1212/CPJ.0000000000001097
2. Bishara H, Bloch S. Systemic intravenous thrombolysis and spinal stroke: a case report and review of the literature. BMJ Neurol Open 2024;6:e000917. DOI: https://doi.org/10.1136/bmjno-2024-000917
3. Al-Salahat A, Dilsaver DB, Jabbar ABA, et al. Outcomes of spinal cord infarction with thrombolysis: a nationwide analysis. Neurocrit Care 2025;42:1102-6.
4. Chandak SN, Chandak N, Kabra D, Baheti N. Spinal cord infarction thrombolysed at seven hours: a case report and review of literature. Cureus 2024;16:e55983. DOI: https://doi.org/10.7759/cureus.55983
5. Al-Salahat A, Dilsaver DB, Jabbar ABA, et al. Outcomes of spinal cord infarction with thrombolysis: a nationwide analysis. Neurocrit Care 2025;42:1102-6. DOI: https://doi.org/10.1007/s12028-025-02251-y
6. Küker W, Weller M, Klose U, et al. Diffusion-weighted MRI of spinal cord infarction--high resolution imaging and time course of diffusion abnormality. J Neurol 2004;251:818-24. DOI: https://doi.org/10.1007/s00415-004-0434-z
7. Thurnher MM, Bammer R. Diffusion-weighted MR imaging (DWI) in spinal cord ischemia. Neuroradiology 2006;48:795-801. DOI: https://doi.org/10.1007/s00234-006-0130-z
8. Ropper AH, Samuels MA, Klein JP. Adams and Victor’s Principles of Neurology. 11th ed. New York: McGraw-Hill; 2019.
9. Netter FH. Atlas of Human Anatomy. 8th ed. Philadelphia: Elsevier; 2023.
10. Wingerchuk DM, Banwell B, Bennett JL, et al. International consensus diagnostic criteria for neuromyelitis optica spectrum disorders. Neurology 2015;85:177-89. DOI: https://doi.org/10.1212/WNL.0000000000001729
11. Duprez TP, Danvoye L, Hernalsteen D, et al. Fibrocartilaginous embolization to the spinal cord: serial MR imaging monitoring and pathologic study. AJNR Am J Neuroradiol 2005;26:496-501.
12. Dubey D, Pittock SJ, Krecke KN, et al. Clinical, radiologic, and prognostic features of myelitis associated with myelin oligodendrocyte glycoprotein autoantibody. JAMA Neurol 2019;76:301-9. DOI: https://doi.org/10.1001/jamaneurol.2018.4053
CRediT authorship contribution
The authors contributed equally to the present paper.
How to Cite

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.




