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• 41 | SRT2104 improves muscle and cognitive outcomes and has the potential to enhance μDys gene therapy in Duchenne muscular dystrophy Laura Lociuro¹, A. Arcari², O. Gjana¹, G. Scolari¹, S.R. Casati^1|2, S. Zecchini², M. Giovarelli², C. Perrotta², C. De Palma¹ | ¹Department of Medical Biotechnology and Translational Medicine (BioMeTra), Università degli Studi di Milano, Segrate (MI), Italy; ²Department of Biomedical and Clinical Sciences "Luigi Sacco" (DIBIC), Università degli Studi di Milano, Italy.

  Interuniversity Institute of Myology

  03-04-2026

  https://doi.org/10.4081/ejtm.2026.15489

  133

• 08 | Combination therapy targeting HDAC8 and SIRT1 improves muscle integrity in a Duchenne muscular dystrophy zebrafish model Sabrina Carbone¹, A. Brix¹, L. Lociuro¹, O. Gjana¹, L. Belleri², M. Schiavone³, A. Marozzi¹, F. Del Bene², C. De Palma¹, A. Pezzotta¹, A. Pistocchi¹ | ¹Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milan, Italy; ²Sorbonne Université, INSERM U968, CNRS UMR 7210, Institut de la Vision, Paris, France; ³Department of Molecular and translational medicine, Università degli Studi di Brescia, Brescia, Italy.

  Interuniversity Institute of Myology

  03-04-2026

  https://doi.org/10.4081/ejtm.2026.15456

  145