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• 43 | Synergistic negative effects of advanced glycation end products and tumor-conditioned medium on C2C12 myotubes and the protective activity of Vaccinium macrocarpon T. Raiteri², Hajar Meskine¹, L. Salvadori¹, M. Paiella², F. Prodam³, F. Riuzzi², N. Filigheddu¹ | ¹Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy; ²Department of Medicine and Surgery, University of Perugia, Perugia, Italy; ³Department of Health Science, University of Piemonte Orientale, Novara, Italy.

  Interuniversity Institute of Myology

  03-04-2026

  https://doi.org/10.4081/ejtm.2026.15491

  87

• 18 | Double-edge sword of ketogenic diet: hepatic improvement at the expense of musculoskeletal health Alessandro Antonioli¹, T. Raiteri², A. Provera¹, S. Reano³, S. Tini¹, S. Sutti¹, N. Filigheddu³, F. Prodam¹ | ¹Department of Health Sciences, University of Piemonte Orientale, Novara, Italy; ²Department of Medicine and Surgery, University of Perugia, Perugia, Italy; ³Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy.

  Interuniversity Institute of Myology

  03-04-2026

  https://doi.org/10.4081/ejtm.2026.15466

  102

• 32 | Trifolium pratense extract mitigates skeletal muscle atrophy: a nutraceutical approach for the prevention of sarcopenia Tommaso Raiteri¹, H. Meskine², M. Paiella¹, A. Trabalzini¹, I. Varfaj⁴, L. Salvadori², F. Riuzzi¹, R. Sardella⁴, F. Orlandi³, N. Filigheddu², G. Sorci¹ | ¹Department of Medicine and Surgery, University of Perugia, Italy; ²Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy; ³Department of Civil and Environmental Engineering, University of Perugia, Italy; ⁴Department of Pharmaceutical Sciences, University of Perugia, Italy.

  Interuniversity Institute of Myology

  03-04-2026

  https://doi.org/10.4081/ejtm.2026.15480

  93

• 30 | The advanced glycation end-products (ages)/rage axis drives sarcobesity, which is restrained by Vaccinium macrocarpon extract Martina Paiella^1|2, L. Salvadori^2|3, T. Raiteri^1|2, G. Gentili^1|2, S. Chiappalupi^1|2, T. Manenti⁴, G. Sorci^1|2, F. Prodam⁵, N. Filigheddu^2|3, F. Riuzzi^1|2 | ¹Dept. Medicine and Surgery, Univ. Perugia, Perugia, Italy; ²Interuniversity Institute of Myology (IIM), Perugia, Italy; ³Dept. Translational Medicine, Univ. Piemonte Orientale, Novara, Italy; ⁴Laboratori Biokyma srl, Anghiari, Italy; ⁵Dept. Health Science, Univ. Piemonte Orientale, Novara, Italy.

  Interuniversity Institute of Myology

  03-04-2026

  https://doi.org/10.4081/ejtm.2026.15478

  97

• 45 | Interleukin-4 prevents cancer-induced muscle wasting and promotes exercise-like metabolic adaptations Giacomo Rubini¹, E. E. Cappellato¹, L. C. Botinas¹, S. Reano², N. Filigheddu², A. Bonetto³, F. Penna¹, P. Costelli ¹ | ¹Dept. of Clinical and Biological Sciences, University of Turin, Italy; ²Dept. of Translational Medicine, University of Piemonte Orientale, Italy; ³Dept. of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

  Interuniversity Institute of Myology

  03-04-2026

  https://doi.org/10.4081/ejtm.2026.15493

  98