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• 46 | Investigating the impact of the tumor secretome on in vitro human skeletal and cardiac muscle models of cancer-induced cachexia

  Ashley Ju-Wei Wang¹, L. Yedigaryan ^1|2, M. Campaner Socias¹, J. Zhang¹, F. Palmieri³, L. Rinvenuto¹, V. Marini¹, R. Squecco³, M. Seelaender⁴, M. Sampaolesi^1|5 | ¹Laboratory of Translational Cardiomyology, Stem Cell Institute Leuven, Department of Development and Regeneration, KU Leuven, Leuven, Belgium; ²IGBMC (Institut de Génétique et de Biologie Moléculaire et Cellulaire), Inserm U1258, CNRS UMR7104, Université de Strasbourg, Illkirch, France; ³Department of Experimental and Clinical Medicine, Section of Physiological Sciences, University of Florence, Florence, Italy; ⁴Cancer Metabolism Research Group, Institute of Biomedical Sciences, University of São Paulo, São Paulo SP, Brazil; ⁵Histology and Medical Embryology Unit, Department of Anatomy, Histology, Forensic Medicine and Orthopaedics, Sapienza University of Rome, Rome, Italy. | Correspondence to A. Ju-Wei Wang and M. Sampaolesi, ashley.wang@kuleuven.be; maurilio.sampaolesi@kuleuven.be.

  Interuniversity Institute of Myology

  03-04-2026

  DOI https://doi.org/10.4081/ejtm.2026.15494

  • 316 abstract views

• 11 | Human immortalized myoblasts/induced pluripotent stem cell derived skeletal muscle model to investigate cystinosis myopathy

  Jianhao Zhang¹, R. Mora De La Serna², M. Smits², V. Marini¹, A. Wang¹, M. Biglietto¹, M. Campaner Socias¹, L. Rinvenuto¹, Z. Ge¹, R. Gijsbers^2|3, M. Sampaolesi^1|4 | ¹Translational Cardiomyology Laboratory, Stem Cell and Developmental Biology, Department of Development and Regeneration, KU Leuven, Leuven, Belgium; ²Laboratory for Molecular Virology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium; ³Leuven Viral Vector Core, KU Leuven, Leuven, Belgium; ⁴Histology and Medical Embryology Unit, Department of Anatomy, Histology, Forensic Medicine and Orthopedics, Sapienza University of Rome, Rome, Italy.

  Interuniversity Institute of Myology

  03-04-2026

  DOI https://doi.org/10.4081/ejtm.2026.15459

  • 273 abstract views

• 13 | Generation of human stem cell-derived cardiac in vitro models to investigate the role of epicardial activation in adverse cardiac remodeling

  Margalida Campaner Socias¹, V. Marini¹, L. Rinvenuto¹, A. Wang¹, J. Zhang¹, S. Morri¹, D. Stalkopf¹, R. Oida¹, B. Sampaio¹, M. Sampaolesi^1|2 | ¹Laboratory of Translational Cardiomyology, Stem Cell and Developmental Biology Unit, Department of Development and Regeneration, KU Leuven, Leuven, Belgium; ²Histology and Medical Embryology Unit, Department of Anatomy, Histology, Forensic Medicine and Orthopaedics, Sapienza University of Rome, Rome, Italy.

  Interuniversity Institute of Myology

  03-04-2026

  DOI https://doi.org/10.4081/ejtm.2026.15461

  • 240 abstract views