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• 28 | Impairment of skeletal muscle force and mitochondrial respiratory capacity precedes muscle mass loss in an aged murine model of diet-induced obesity Clara Sciorati¹, R. De Lorenzo^1|2, A. Avola¹, M. Giovarelli³, C. De Palma³, E. Clementi³, C. Lanzani¹, P. Rovere-Querini^1|2 | ¹IRCCS San Raffaele Hospital Scientific Institute, Milan, Italy; ²Vita-Salute San Raffaele University, Milan, Italy; ³Department of Biomedical and Clinical Science, University of Milan, Italy.

  Interuniversity Institute of Myology

  03-04-2026

  https://doi.org/10.4081/ejtm.2026.15476

  166

• 41 | SRT2104 improves muscle and cognitive outcomes and has the potential to enhance μDys gene therapy in Duchenne muscular dystrophy Laura Lociuro¹, A. Arcari², O. Gjana¹, G. Scolari¹, S.R. Casati^1|2, S. Zecchini², M. Giovarelli², C. Perrotta², C. De Palma¹ | ¹Department of Medical Biotechnology and Translational Medicine (BioMeTra), Università degli Studi di Milano, Segrate (MI), Italy; ²Department of Biomedical and Clinical Sciences "Luigi Sacco" (DIBIC), Università degli Studi di Milano, Italy.

  Interuniversity Institute of Myology

  03-04-2026

  https://doi.org/10.4081/ejtm.2026.15489

  137