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• 46 | Investigating the impact of the tumor secretome on in vitro human skeletal and cardiac muscle models of cancer-induced cachexia Ashley Ju-Wei Wang¹, L. Yedigaryan ^1|2, M. Campaner Socias¹, J. Zhang¹, F. Palmieri³, L. Rinvenuto¹, V. Marini¹, R. Squecco³, M. Seelaender⁴, M. Sampaolesi^1|5 | ¹Laboratory of Translational Cardiomyology, Stem Cell Institute Leuven, Department of Development and Regeneration, KU Leuven, Leuven, Belgium; ²IGBMC (Institut de Génétique et de Biologie Moléculaire et Cellulaire), Inserm U1258, CNRS UMR7104, Université de Strasbourg, Illkirch, France; ³Department of Experimental and Clinical Medicine, Section of Physiological Sciences, University of Florence, Florence, Italy; ⁴Cancer Metabolism Research Group, Institute of Biomedical Sciences, University of São Paulo, São Paulo SP, Brazil; ⁵Histology and Medical Embryology Unit, Department of Anatomy, Histology, Forensic Medicine and Orthopaedics, Sapienza University of Rome, Rome, Italy. | Correspondence to A. Ju-Wei Wang and M. Sampaolesi, ashley.wang@kuleuven.be; maurilio.sampaolesi@kuleuven.be.

  Interuniversity Institute of Myology

  03-04-2026

  https://doi.org/10.4081/ejtm.2026.15494

  106