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46 | Investigating the impact of the tumor secretome on in vitro human skeletal and cardiac muscle models of cancer-induced cachexia Ashley Ju-Wei Wang1, L. Yedigaryan 1|2, M. Campaner Socias1, J. Zhang1, F. Palmieri3, L. Rinvenuto1, V. Marini1, R. Squecco3, M. Seelaender4, M. Sampaolesi1|5 | 1Laboratory of Translational Cardiomyology, Stem Cell Institute Leuven, Department of Development and Regeneration, KU Leuven, Leuven, Belgium; 2IGBMC (Institut de Génétique et de Biologie Moléculaire et Cellulaire), Inserm U1258, CNRS UMR7104, Université de Strasbourg, Illkirch, France; 3Department of Experimental and Clinical Medicine, Section of Physiological Sciences, University of Florence, Florence, Italy; 4Cancer Metabolism Research Group, Institute of Biomedical Sciences, University of São Paulo, São Paulo SP, Brazil; 5Histology and Medical Embryology Unit, Department of Anatomy, Histology, Forensic Medicine and Orthopaedics, Sapienza University of Rome, Rome, Italy. | Correspondence to A. Ju-Wei Wang and M. Sampaolesi, ashley.wang@kuleuven.be; maurilio.sampaolesi@kuleuven.be.
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13 | Generation of human stem cell-derived cardiac in vitro models to investigate the role of epicardial activation in adverse cardiac remodeling Margalida Campaner Socias1, V. Marini1, L. Rinvenuto1, A. Wang1, J. Zhang1, S. Morri1, D. Stalkopf1, R. Oida1, B. Sampaio1, M. Sampaolesi1|2 | 1Laboratory of Translational Cardiomyology, Stem Cell and Developmental Biology Unit, Department of Development and Regeneration, KU Leuven, Leuven, Belgium; 2Histology and Medical Embryology Unit, Department of Anatomy, Histology, Forensic Medicine and Orthopaedics, Sapienza University of Rome, Rome, Italy.
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04 | CD90 identifies distinct fractions of muscle stem cells with different modalities of activation and quiescence maintenance Lorenzo Marramiero1|2, S. Di Savino1|2, E. Kheir1|2, M. Libergoli1|2, S. Metti3, A. Zola1|2, J.B. Jensen4|5, J.Wang5, N. Jessen4|5|6, F. Florio1|2, F. Murganti1|2, M. Belicchi 7|8, C. Villa8, K. Vissing9, M. Verma10, L. Giordani11, P. Bonaldo3, Y. Torrente7|8, J. Farup4, S. Biressi1|2 | 1Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Povo, Italy; 2Dulbecco Telethon Institute at University of Trento, Povo, Italy; 3Department of Molecular Medicine, University of Padova, Italy; 4Department of Biomedicine, Aarhus University, Denmark; 5Steno Dia,5betes Center Aarhus, Denmark; 6Department of Clinical Pharmacology, Aarhus University Hospital, Denmark; 7Neurology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; 8Stem Cell Laboratory, Dino Ferrari Center, Department of Pathophysiology and Transplantation, University of Milan, Italy; 9Department of Public Health, Aarhus University, Denmark; 10University of Texas Southwestern Medical Center, Dallas, USA; 11Centre de Recherche en Myologie, Sorbonne Universités,Paris, France.
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11 | Human immortalized myoblasts/induced pluripotent stem cell derived skeletal muscle model to investigate cystinosis myopathy Jianhao Zhang1, R. Mora De La Serna2, M. Smits2, V. Marini1, A. Wang1, M. Biglietto1, M. Campaner Socias1, L. Rinvenuto1, Z. Ge1, R. Gijsbers2|3, M. Sampaolesi1|4 | 1Translational Cardiomyology Laboratory, Stem Cell and Developmental Biology, Department of Development and Regeneration, KU Leuven, Leuven, Belgium; 2Laboratory for Molecular Virology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium; 3Leuven Viral Vector Core, KU Leuven, Leuven, Belgium; 4Histology and Medical Embryology Unit, Department of Anatomy, Histology, Forensic Medicine and Orthopedics, Sapienza University of Rome, Rome, Italy.
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