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• 07 | Role of GDF5 on macrophage polarization in the maintenance of muscle mass and function and during aging Maxime Gelin¹, E. Hemery¹, F. Truffault¹, G. Juban², C. Perrotta³, F. Pietri-Rouxel¹, M. Traoré¹, S. Falcone¹ | ¹Centre de Recherche en Myologie – U974 INSERM, Sorbonne Université, Institut de Myologie, Paris, France; ²Institut NeuroMyoGène, Physiopathologie et Génétique du Neurone et du Muscle Université Claude Bernard Lyon 1, CNRS U5261, Inserm U1315, University Lyon, Lyon, France; ³Department of Biomedical and Clinical Sciences Università degli Studi di Milano, Milan, Italy. | M. Traoré and S. Falcone contributed equally to this work and corresponding authors. s.falcone@institut-myologie.org; m.traore@institut-myologie.org.

  Interuniversity Institute of Myology

  03-04-2026

  https://doi.org/10.4081/ejtm.2026.15455

  98

• 41 | SRT2104 improves muscle and cognitive outcomes and has the potential to enhance μDys gene therapy in Duchenne muscular dystrophy Laura Lociuro¹, A. Arcari², O. Gjana¹, G. Scolari¹, S.R. Casati^1|2, S. Zecchini², M. Giovarelli², C. Perrotta², C. De Palma¹ | ¹Department of Medical Biotechnology and Translational Medicine (BioMeTra), Università degli Studi di Milano, Segrate (MI), Italy; ²Department of Biomedical and Clinical Sciences "Luigi Sacco" (DIBIC), Università degli Studi di Milano, Italy.

  Interuniversity Institute of Myology

  03-04-2026

  https://doi.org/10.4081/ejtm.2026.15489

  87