Balbiani granules as a model for studying RNA synthesis and processing


https://doi.org/10.4081/microscopie.2013.4989
Vol. 20 No. 2 (2013)
Submitted: 16 January 2015
Accepted: 16 January 2015
Published: 30 September 2013
cell nucleus, RNA transcription, Balbiani granules.
Abstract Views: 465
PDF: 766
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

  • A. Demicheli Dipartimento di Biologia e Biotecnologie “Lazzaro Spallanzani”, Laboratorio di Biologia Cellulare e Neurobiologia, Università di Pavia, Pavia, Italy.
  • V. Galimberti Dipartimento di Biologia e Biotecnologie “Lazzaro Spallanzani”, Laboratorio di Biologia Cellulare e Neurobiologia, Università di Pavia, Pavia, Italy.
  • M. Biggiogera
    marcobig@unipv.it
    Dipartimento di Biologia e Biotecnologie “Lazzaro Spallanzani”, Laboratorio di Biologia Cellulare e Neurobiologia, Università di Pavia, Pavia, Italy.
We investigated, by ultrastructural immunocytochemistry, the localization and molecular composition of Balbiani granules from Chironomus thummi polytene chromosomes. The salivary gland cells produce huge amounts of RNA coding for a single protein, hence the mRNAs have all the same length and the resulting granules share identical characteristics. Our results show the localization of cleavage, polyadenylation and splicing factors on the nascent perichromatin fibrils and, more rarely, on the already structured Balbiani granules.

Demicheli, A., Galimberti, V., & Biggiogera, M. (2013). Balbiani granules as a model for studying RNA synthesis and processing. Microscopie, 20(2), 44–48. https://doi.org/10.4081/microscopie.2013.4989

PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.

An Open Access Publication is one that meets the following two conditions:

  1. the author(s) and copyright holder(s) grant(s) to all users a free, irrevocable, worldwide, perpetual right of access to, and a license to copy, use, distribute, transmit and display the work publicly and to make and distribute derivative works, in any digital medium for any responsible purpose, subject to proper attribution of authorship, as well as the right to make small numbers of printed copies for their personal use.
  2. a complete version of the work and all supplemental materials, including a copy of the permission as stated above, in a suitable standard electronic format is deposited immediately upon initial publication in at least one online repository that is supported by an academic institution, scholarly society, government agency, or other well-established organization that seeks to enable open access, unrestricted distribution, interoperability, and long-term archiving.

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.

Downloads

Download data is not yet available.

Citations

Crossref
Scopus
Google Scholar
Europe PMC