Brief report on cognitive function and corticosteroid therapy in elderly
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Alberto Castagna
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albertocastagna@tiscali.it
Center for Cognitive Disorders and Dementia, Azienda Sanitaria Provinciale di Catanzaro, Italy.
- Giuseppe Coppolino Renal Unit, Department of Health Sciences, Magna Graecia University, Catanzaro, Italy.
- Carmen Ruberto Center for Cognitive Disorders and Dementia, Azienda Sanitaria Provinciale di Catanzaro, Italy.
- Giovanni Ruotolo Geriatric Unit, Pugliese-Ciaccio General Hospital, Catanzaro, Italy.
- Ciro Manzo Internal and Geriatric Medicine Department Azienda Sanitaria Locale Napoli 3 sud, Rheumatologic outpatient clinic and geronthorheumatologic service, Mariano Lauro hospital, Sant’Agnello (NA), Italy.
Abstract
Glucocorticoids (GCs) are drugs commonly used for the treatment of a great number of acute or chronic pathological conditions. In a cross-sectional study we analyze a cohort of elderly patients treated for at least four weeks with a glucocorticoid (GC), exactly prednisone therapy, for a renal or rheumatological condition pointing out on functional, mental and clinical status. The main purpose was to assess change in cognitive performances. Corticosteroids administration also at low dosage in older subjects could enhance cognitive function. This observation should be proved in larger population and underlying mechanisms studied in deep.
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