https://doi.org/10.4081/gc.2026.14933
Pasteurella canis sepsis with fatal outcome in the frail older: a case report
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Published: 3 April 2026
Pasteurella canis typically causes wound infections following dog bites, while invasive infections are uncommon. Within invasive infections, bacteremia (the presence of bacteria in the bloodstream) must be differentiated from sepsis (the organ dysfunction caused by a dysregulated immunological response to infection).
Sepsis and heart failure interact in a continuum where sepsis-induced cardiomyopathy is triggered by acute systemic inflammation, whereas preexisting heart failure increases susceptibility to sepsis and mortality.
We present the case of an 87-year-old frail woman admitted with heart failure. Blood cultures taken after a febrile episode resulted positive for P. canis. Response to piperacillin/tazobactam was satisfactory, although the patient died from heart failure. She did not report a history of a dog bite; therefore, we speculated that P. canis spread through respiratory secretions of a dog known to the patient, causing pneumonia (documented at a computed tomography scan) followed by sepsis.
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Ibarz M, Haas LEM, Ceccato A, et al. The critically ill older patient with sepsis: a narrative review. Ann Intensive Care 2024;14:6. DOI: https://doi.org/10.1186/s13613-023-01233-7
Martín S, Pérez A, Aldecoa C. Sepsis and immunosenescence in the elderly patient: a review. Front Med 2017;4:20. DOI: https://doi.org/10.3389/fmed.2017.00020
Vitali A, Dini S, Cozza M, et al. Sepsis and septic shock in geriatrics. Geriatric Care 2024;10:11709. DOI: https://doi.org/10.4081/gc.2024.11709
Chatelier E, Mahieu R, Hamel JF, et al. Pasteurella bacteraemia: Impact of comorbidities on outcome, based on a case series and literature review. Int J Infect Dis 2020;92:89-96. DOI: https://doi.org/10.1016/j.ijid.2020.01.003
Holst E, Rollof J, Larsson L, et al. Characterization of Pasteurella species recovered from infected humans. J Clin Microbiol 1992;30:2984-7. DOI: https://doi.org/10.1128/jcm.30.11.2984-2987.1992
Davis BL, Rasnake M. Pasteurella canis/oralis: a tale of the immunocompromised. Cureus 2024;16:e64227. DOI: https://doi.org/10.7759/cureus.64227
Albert TJ, Stevens DL. The first case of Pasteurella canis bacteremia: a cirrhotic patient with an open leg wound. Infection 2010;38:483-5. DOI: https://doi.org/10.1007/s15010-010-0040-1
Faceira A, Póvoa S, Souteiro P, et al. Human infection by Pasteurella canis - a case report. Porto Biomed J 2017;2:63-5. DOI: https://doi.org/10.1016/j.pbj.2017.01.005
Nascimento B, Gomes AG, Coelho CN, et al. Septic arthritis and bacteremia due to infection by Pasteurella canis. Cureus 2021;13:e19478. DOI: https://doi.org/10.7759/cureus.19478
Bhat S, Acharya PR, Biranthabail D, et al. A case of lower respiratory tract infection with canine-associated Pasteurella canis in a patient with chronic obstructive pulmonary disease. J ClinDiag Res 2015;9:DD03-4. DOI: https://doi.org/10.7860/JCDR/2015/13900.6351
Casallas-Rivera M, Faccini-Martínez A, Perdomo-Beltrán N, et al. Septicemia hemorrágica y empiema pleural por Pasteurella canis. Rev Chil Infectol 2016;33:85-8. [Article in Spanish]. DOI: https://doi.org/10.4067/S0716-10182016000100015
Kaftandzieva A, Peneva M, Petrovska B, et al. Pasteurella canis as a cause of soft-tissue infection after dog bite: a case report. Maced J Med Sci 2013;6:74-8. DOI: https://doi.org/10.3889/MJMS.1857-5773.2013.0279
Kim B, Pai H, Lee KH, et al. Identification of Pasteurella canis in a soft tissue infection caused by a dog bite: the first report in Korea. Ann Lab Med 2016;36:617-9. DOI: https://doi.org/10.3343/alm.2016.36.6.617
Ramiro GV, Gregorio AA, Luis GVJ, et al. Pasteurella canis as a cause of septic arthritis and soft tissue infection after sheep bite: a case report. Global J Med Clin Case Report 2016;3:012-4. DOI: https://doi.org/10.17352/2455-5282.000025
Kaushal K, Belachew W. “Whodunit”: urinary tract infection by Pasteurella canis. Proceedings of UCLA Health, 2021;25(1).
CRediT authorship contribution
Carolina Nani: concepts, definition of intellectual content, literature search, manuscript preparation, editing, and review. Emma Esposito: literature search, manuscript preparation, editing, and review. Laura Carassale: editing and review.
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