Symmetrical peripheral gangrene in a patient with septic shock and a multi-drug resistant <i>Klebsiella pneumoniae</i> infection

Giovanni Carbone; Immacolata Sepe; Maria Rosaria Fiorentino; Elisa Salsano; Federico Ruggiero; Michele Schiavone; Dalila Bruno; Filomena Micillo; Nicola Vargas

doi:10.4081/gc.2023.11377

Authors

Giovanni Carbone Department of Translational Medical Sciences, University of Naples Federico II, Italy. https://orcid.org/0009-0006-7166-114X
Immacolata Sepe Department of Translational Medical Sciences, University of Naples Federico II, Italy. https://orcid.org/0009-0006-0021-9231
Maria Rosaria Fiorentino Department of Translational Medical Sciences, University of Naples Federico II, Italy.
Elisa Salsano Geriatric and Intensive Geriatric Care Unit, San Giuseppe Moscati Hospital, Avellino, Italy. https://orcid.org/0009-0001-1493-3392
Federico Ruggiero Department of Translational Medical Sciences, University of Naples Federico II, Italy. https://orcid.org/0009-0002-4710-4328
Michele Schiavone Geriatric and Intensive Geriatric Care Unit, San Giuseppe Moscati Hospital, Avellino, Italy.
Dalila Bruno Geriatric and Intensive Geriatric Care Unit, San Giuseppe Moscati Hospital, Avellino, Italy. https://orcid.org/0000-0002-3817-5004
Filomena Micillo Geriatric and Intensive Geriatric Care Unit, San Giuseppe Moscati Hospital, Avellino, Italy.
Nicola Vargas
vargasnicola32@gmail.com
Geriatric and Intensive Geriatric Care Unit, San Giuseppe Moscati Hospital, Avellino, Italy.

Symmetrical peripheral gangrene (SPG) can sometimes occur without definite disseminated intravascular coagulation. The differential diagnosis comprises the exclusion of many non-infectious diseases and the effort to isolate the microbic agent in the case of septic shock. Between bacterial causes, Klebsiella pneumoniae is one of the bacteria that can trigger SPG through hypervirulence and hypercoagulopathy mechanisms. We report a case of SPG associated with septic shock and a multi-drug resistant K. pneumoniae infection.

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Carbone, G., Sepe, I., Fiorentino, M. R., Salsano, E., Ruggiero, F., Schiavone, M., Bruno, D., Micillo, F., & Vargas, N. (2023). Symmetrical peripheral gangrene in a patient with septic shock and a multi-drug resistant <i>Klebsiella pneumoniae</i> infection. Geriatric Care, 9(1). https://doi.org/10.4081/gc.2023.11377