Symmetrical peripheral gangrene in a patient with septic shock and a multi-drug resistant Klebsiella pneumoniae infection

Authors

  • Giovanni Carbone Department of Translational Medical Sciences, University of Naples Federico II https://orcid.org/0009-0006-7166-114X
  • Immacolata Sepe Department of Translational Medical Sciences, University of Naples Federico II https://orcid.org/0009-0006-0021-9231
  • Maria Rosaria Fiorentino Department of Translational Medical Sciences, University of Naples Federico II
  • Elisa Salsano Geriatric and Intensive Geriatric Care Unit, San Giuseppe Moscati Hospital, Avellino https://orcid.org/0009-0001-1493-3392
  • Federico Ruggiero Department of Translational Medical Sciences, University of Naples Federico II https://orcid.org/0009-0002-4710-4328
  • Michele Schiavone Geriatric and Intensive Geriatric Care Unit, San Giuseppe Moscati Hospital, Avellino
  • Dalila Bruno Geriatric and Intensive Geriatric Care Unit, San Giuseppe Moscati Hospital, Avellino https://orcid.org/0000-0002-3817-5004
  • Filomena Micillo Geriatric and Intensive Geriatric Care Unit, San Giuseppe Moscati Hospital, Avellino
  • Nicola Vargas Geriatric and Intensive Geriatric Care Unit, San Giuseppe Moscati Hospital, Avellino

DOI:

https://doi.org/10.4081/gc.2023.11377

Keywords:

Septic shock, septic microemboli, klebsiella pneumonia, gangrene, elderly

Abstract

Symmetrical peripheral gangrene (SPG) can sometimes occur without definite disseminated intravascular coagulation. The differential diagnosis comprises the exclusion of many non-infectious diseases and the effort to isolate the microbic agent in the case of septic shock. Between bacterial causes, Klebsiella pneumoniae is one of the bacteria that can trigger SPG through hypervirulence and hypercoagulopathy mechanisms. We report a case of SPG associated with septic shock and a multi-drug resistant K. pneumoniae infection.

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References

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Foead AI, Mathialagan A, Varadarajan R, Larvin M. Management of symmetrical peripheral gangrene. Indian J Crit Care Med 2018;22:870-4. DOI: https://doi.org/10.4103/ijccm.IJCCM_379_18

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Kashyap R, Behl RK, Mahajan S, et al. Symmetrical peripheral gangrene due to viral gastroenteritis. J Assoc Physicians India 2004;52:500-1.

Yoo J, Min J, Kwon S, et al. Symmetrical peripheral gangrene complicating klebsiella pneumoniae sepsis associated with antiphospholipid antibodies. Ann Rheum Dis 2004;63:459-60. DOI: https://doi.org/10.1136/ard.2003.012542

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Published

28-08-2023

Issue

Vol. 9 No. 1 (2023)

Section

Case Reports

License

Copyright (c) 2023 the Author(s)

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How to Cite

Symmetrical peripheral gangrene in a patient with septic shock and a multi-drug resistant Klebsiella pneumoniae infection. (2023). Geriatric Care, 9(1). https://doi.org/10.4081/gc.2023.11377