Case Reports Open access

Symmetrical peripheral gangrene in a patient with septic shock and a multi-drug resistant Klebsiella pneumoniae infection

Authors

Published
28 August 2023
Section
Case Reports
DOI
10.4081/gc.2023.11377

Abstract

Symmetrical peripheral gangrene (SPG) can sometimes occur without definite disseminated intravascular coagulation. The differential diagnosis comprises the exclusion of many non-infectious diseases and the effort to isolate the microbic agent in the case of septic shock. Between bacterial causes, Klebsiella pneumoniae is one of the bacteria that can trigger SPG through hypervirulence and hypercoagulopathy mechanisms. We report a case of SPG associated with septic shock and a multi-drug resistant K. pneumoniae infection.

Keywords

References

  1. Warkentin TE. Ischemic limb gangrene with pulses. N Engl J Med 2015;373:642-55. DOI: https://doi.org/10.1056/NEJMra1316259
  2. Foead AI, Mathialagan A, Varadarajan R, Larvin M. Management of symmetrical peripheral gangrene. Indian J Crit Care Med 2018;22:870-4. DOI: https://doi.org/10.4103/ijccm.IJCCM_379_18
  3. WHO. Global Priority List of Antibiotic-resistant Bacteria to Guide Research, Discovery, and Development of New Antibiotics. Available from: https://www.quotidianosanita.it/allegati/allegato4135670.pdf.
  4. Kashyap R, Behl RK, Mahajan S, et al. Symmetrical peripheral gangrene due to viral gastroenteritis. J Assoc Physicians India 2004;52:500-1.
  5. Yoo J, Min J, Kwon S, et al. Symmetrical peripheral gangrene complicating klebsiella pneumoniae sepsis associated with antiphospholipid antibodies. Ann Rheum Dis 2004;63:459-60. DOI: https://doi.org/10.1136/ard.2003.012542
  6. Kamal F, Williams G, Akbar H, et al. Klebsiella pneumoniae liver abscess: a case report and review of literature. Cureus 2017;9:e970. DOI: https://doi.org/10.7759/cureus.970

Metrics

Citations and online attention from Dimensions, Altmetric and PlumX.

PlumX Metrics

License

Copyright (c) 2023 the Author(s)

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.