The role of comprehensive geriatric assessment in older patients affected by knee osteoarthritis: a systematic review

Nicola Veronese; Anna Fazzari; Maela Caudal; Maria Cristina Polidori; Eva Topinkova; Francesco Mattace Raso; Marina Barbagelata; Mario Barbagallo; Alberto Pilotto

doi:10.4081/gc.2022.11049

Authors

Nicola Veronese
nicola.veronese@unipa.it
Geriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, Palermo, Italy. https://orcid.org/0000-0002-9328-289X
Anna Fazzari Geriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, Palermo, Italy. https://orcid.org/0000-0002-6497-773X
Maela Caudal St. Marien Hospital (Cellitinnen), Cologne, Germany. https://orcid.org/0000-0001-5882-684X
Maria Cristina Polidori Department of Medicine II, University Hospital of Cologne, Germany.
Eva Topinkova Department of Geriatrics, 1st Faculty of Medicine, Charles University, Prague, Czech Republic; General Faculty Hospital, Prague, Czech Republic; Faculty of Health and Social Sciences, University of South Bohemia, České Budejovice, Czechia. https://orcid.org/0000-0002-6786-4116
Francesco Mattace Raso Department of Internal Medicine, Geriatrics Unit, Erasmus MC Rotterdam, Netherlands.
Marina Barbagelata Department of Geriatric Care, OrthoGeriatrics and Rehabilitation Hospital Board of the Galliera Hospitals of Genoa, Genoa, Italy. https://orcid.org/0000-0002-3973-5843
Mario Barbagallo Geriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, Palermo, Italy.
Alberto Pilotto Department of Geriatric Care, OrthoGeriatrics and Rehabilitation Hospital Board of the Galliera Hospitals of Genoa, Genoa, Italy.

Osteoarthritis (OA) is one of the most common musculoskeletal diseases and highly prevalent in older people. Whilst the management of knee OA is usually multidisciplinary, the use of comprehensive geriatric assessment (CGA) for this condition is still limited. Given this background, with this systematic review, we summarized the current literature regarding the importance of CGA in people affected by knee OA. A systematic search across several databases was run until 10^th April 2022 and updated on 21^st November 2022 for any study investigating the use of CGA in patients with knee OA. The data were summarized descriptively. Among 295 articles initially included, three studies made in the context of the osteoarthritis initiative (OAI) were included. All the three studies used the OAI multidimensional prognostic index (MPI), a composite score derived from the CGA. Higher MPI values were associated with a higher risk of falls, cardiovascular conditions, and fractures across a follow-up period of 8 years and after adjusting for potential confounders. In conclusion, in this systematic review we summarized the current evidence of CGA in knee OA, finding that the MPI, a CGA derived tool, could be useful to early find people at higher risk of conditions that are associated with knee OA and therefore that can be the target of personalized interventions for preventing these conditions.

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Veronese, N., Fazzari, A., Caudal, M., Polidori, M. C., Topinkova, E., Mattace Raso, F., Barbagelata, M., Barbagallo, M., & Pilotto, A. (2022). The role of comprehensive geriatric assessment in older patients affected by knee osteoarthritis: a systematic review. Geriatric Care, 8(3). https://doi.org/10.4081/gc.2022.11049