Recreation use of phosphodiesterase type 5 inhibitors, the other side of erectile dysfunction


Published: May 29, 2023
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Authors

  • Giovanni Maria Fusco Department of Neurosciences, Reproductive Sciences and Odontostomatology, Urology Unit, University of Naples "Federico II", Naples, Italy.
  • Luigi Cirillo Department of Neurosciences, Reproductive Sciences and Odontostomatology, Urology Unit, University of Naples "Federico II", Naples, Italy.
  • Francesco Mastrangelo Department of Neurosciences, Reproductive Sciences and Odontostomatology, Urology Unit, University of Naples "Federico II", Naples, Italy.
  • Francesco Romano Department of Neurosciences, Reproductive Sciences and Odontostomatology, Urology Unit, University of Naples "Federico II", Naples, Italy.
  • Ernesto Di Mauro Department of Neurosciences, Reproductive Sciences and Odontostomatology, Urology Unit, University of Naples "Federico II", Naples, Italy.
  • Gianluigi Cacace Department of Neurosciences, Reproductive Sciences and Odontostomatology, Urology Unit, University of Naples "Federico II", Naples, Italy.
  • Gianluca Spena Department of Neurosciences, Reproductive Sciences and Odontostomatology, Urology Unit, University of Naples "Federico II", Naples, Italy. https://orcid.org/0000-0002-6714-9315
  • Annamaria Iannicelli Department of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
  • Corrado Aniello Franzese ASL Napoli 3 Sud, Naples, Italy.
  • Vincenzo Mirone Department of Neurosciences, Reproductive Sciences and Odontostomatology, Urology Unit, University of Naples "Federico II", Naples, Italy.
  • Roberto La Rocca Department of Neurosciences, Reproductive Sciences and Odontostomatology, Urology Unit, University of Naples "Federico II", Naples, Italy.
  • Luigi Napolitano Department of Neurosciences, Reproductive Sciences and Odontostomatology, Urology Unit, University of Naples "Federico II", Naples, Italy. https://orcid.org/0000-0003-2036-0356

To the Editor, In 1998 Sildenafil was approved by the Food and Drug Administration as first line therapy for erectile dysfunction. Since then, phosphodiesterase type 5 inhibitors (PDE5i) represent the first-line treatment of erectile dysfunction (ED), improving physiological erectile function, sexual orgasmic function, psychological self-esteem, couples’ relationship, and quality of life. [...]


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Napolitano L, Cirillo L, Fusco GM, et al. Natural treatments for erectile dysfunction: A focus on mobile health applications. Arch Ital Urol Androl. 2022; 94:373-374. DOI: https://doi.org/10.4081/aiua.2022.3.373

Fusco, G. M., Cirillo, L., Mastrangelo, F., Romano, F., Di Mauro, E., Cacace, G., Spena, G., Iannicelli, A., Franzese, C. A., Mirone, V., La Rocca, R., & Napolitano, L. (2023). Recreation use of phosphodiesterase type 5 inhibitors, the other side of erectile dysfunction. Archivio Italiano Di Urologia E Andrologia, 95(2). https://doi.org/10.4081/aiua.2023.11350

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