Valutazione del nuovo sistema automatizzato Triturus - Grifols nella diagnosi sierologica delle infezioni da complesso ToRCH e da virus di Epstein Barr

The laboratory diagnosis of infections belonging to the ToRCH complex is mainly based of the determination of the immune status to each individual microrganism. In this report, the diagnostic performance of a new automated EIA plates processor system (SeraQuest - GRIFOLS, Pisa, Italy) has been compared with other automaed methods: Enzygnost (Dade behring, Marburg, Germany), EIA Well (RADIM, Pomezia, Italy),VIDAS (bioMériuex, Marcy l’etoile, France). In addition, the diagnostic performance of SeraQuest has also been evaluated for the detection of specific immune response to Epstein Barr virus, in comparison with a conventional EIA test (Delta, Pomezia, Italy) and with an immunoblotting method (Genelabs - AlfaBiotech, Milan, Italy).The overal evaluation of SeraQuest demonstrated that this test has sensitivity and specificity well comaparable with those of the other methods studied and that could be used as an alternative test in the serological diagnosis of ToRCH and EBV infections.