https://doi.org/10.4081/mm.2025.13838
Dengue virus infection: a study on clinical, haematological, and radiological profiles of patients admitted to a tertiary care hospital in Central India
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Published: 2 March 2026
Background: dengue fever is an emerging mosquito-borne viral infection with a broad clinical spectrum ranging from mild febrile illness to severe dengue haemorrhagic fever and dengue shock syndrome. Haematological and radiological assessments play a crucial role in the early detection and management of severe cases.
Materials and Methods: this cross-sectional study was conducted at the Government Medical College, Nagpur, Maharashtra, India, from July 2022 to June 2024. 429 patients with acute febrile illness were screened for dengue infection using NS1 antigen, IgM, and IgG ELISA. Clinical data, haematological parameters, and radiological findings were collected to evaluate disease severity.
Results: out of 429 suspected cases, 25.41% were confirmed dengue-positive. Common clinical features included fever (100%), myalgia/arthralgia (77.98%), nausea/vomiting (63.3%), and headache (62.39%). Haemorrhagic manifestations were observed in 36.7% of cases, with petechiae being the most common. Radiological findings such as ascites (21.1%), hepatomegaly (18.35%), and gallbladder wall oedema (13.76%) were notable indicators of severe disease. Among the positive cases, 57.8%, 36.7% and 5.5% were classified as DHF, DF, and DSS respectively.
Conclusions: clinical presentation combined with haematological and radiological parameters are valuable for early diagnosis and management of dengue infection. Early recognition of warning signs and monitoring key indicators can help reduce dengue-related morbidity and mortality.
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