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Oxygen-ozone therapy has been piloted in Italy patients with ischemic heart disease or suffering from myocardial infarction since 1991. Over time, it has been observed that ozone exerts a significant anti-inflammatory and rheological activity: ozone activates the redox system, lowers the pro-inflammatory cytokines16β, TNFα, modulates the NF-KB system, reduces platelet aggregation, and stimulates the release of growth factors. It is because of these characteristics that oxygen-ozone therapy is used in the prevention and treatment of ischemic heart disease and for post-infarction rehabilitation. The case study – a critically ill patient aged 76 with acute myocardial infarction (AMI), suffering from ischemic heart disease and heart attacks, high blood pressure, renal failure, ischemic vascular pluri-infarct CNS disease, Parkinsonism, stroke, neurological bladder disease and debilitating inguinal hernia – after a year and a half of AMI with infusions of autologous blood treated with ozone (GAE), recovered the left ventricular ejection fraction from 33 to 50% and underwent a successful inguinal hernia operation. It appears evident that oxygen ozone therapy using GAE protect the hearts of patients suffering from ischemic heart disease, and is useful during the acute phase of infarctions, as well as for rehabilitating patients who have had an AMI with stenting.
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