Social and political factors affecting public health
Vol. 12 No. s2 (2024): Social and political factors affecting public health
https://doi.org/10.4081/hls.2024.12831

Innovations in cancer diagnosis and treatment: prospects and challenges

Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Received: 22 July 2024
Published: 9 October 2024
1416
Views
619
Downloads
101
HTML

Authors

The research relevance of cancer diagnostics and treatment is determined by its widespread occurrence and the lack of adequate modern diagnostic methods. The study aims to characterise new diagnostic methods, namely screenings in detecting cancer at early stages of development. To achieve this goal, the bibliosemantic and bibliographic methods were used. Main results. Cancer is the leading cause of morbidity and mortality after cardiovascular diseases and injuries in many countries around the world. Various diagnostic and treatment methods are used to combat this problem, including computed tomography, magnetic resonance imaging and positron emission tomography. In addition, modern diagnostic methods such as polymerase chain reaction, mass spectrometry and genomic sequencing play an important role in determining the types of cancer cells and their sensitivity to treatment. These advanced methods can be used to diagnose cancer more accurately and efficiently and choose the most appropriate treatment strategies for each patient. The practical significance of this topic is to ensure appropriate care for patients with cancer: providing high-quality, efficient, fast and minimally invasive diagnostics using the latest methods, as well as implementing a screening system.

Downloads

Download data is not yet available.

Latka K, Kołodziej W, Rajski R, et al. Outpatient spine surgery in Poland: A survey on popularity, challenges, and future perspectives. Risk Manag Healthc Policy 2023;16:1839-48. DOI: https://doi.org/10.2147/RMHP.S425465

Siegel RL, Miller KD, Wagle NS, Jemal A. Cancer statistics, 2023. CA Cancer J Clin 2023;73:17-48. DOI: https://doi.org/10.3322/caac.21763

Merkuri L, Kamberi F, Qorri E, Shapo L. Assessment of the Albanian University female students’ knowledge, attitudes, and practices on cervical cancer. J Infect Dev Ctries 2023;17:534-41. DOI: https://doi.org/10.3855/jidc.18121

Dimitrova M, Lakic D, Petrova G, et al. Comparative analysis of the access to health-care services and breast cancer therapy in 10 Eastern European countries. SAGE Open Med 2020;8:2050312120922029. DOI: https://doi.org/10.1177/2050312120922029

Xhemalaj D, Gradica F, Skenduli I, et al. Lung cancer in Albania. J Thorac Oncol 2023;18:1632-7. DOI: https://doi.org/10.1016/j.jtho.2023.08.023

Filaj V, Jorgaqi E, Byzhyti M. Our experience in the treatment of hemangioma with intense pulsed light laser: A 10 year study in Albania. Dermatol Ther 2021;34:e14880. DOI: https://doi.org/10.1111/dth.14880

Wang H, Meng Q, Qian J, et al. Review: RNA-based diagnostic markers discovery and therapeutic targets development in cancer. Pharmacol Ther 2022;234:108123. DOI: https://doi.org/10.1016/j.pharmthera.2022.108123

Song P, Wu LR, Yan YH, et al. Limitations and opportunities of technologies for the analysis of cell-free DNA in cancer diagnostics. Nat Biomed Eng 2022;6:232-45. DOI: https://doi.org/10.1038/s41551-021-00837-3

Dolatkhah R, Dastgiri S, Jafarabadi MA, et al. Diagnostic accuracy of multitarget stool DNA testing for colorectal cancer screening: A systematic review and meta-analysis. Gastroenterol Hepatol 2022;45:753-66. DOI: https://doi.org/10.1016/j.gastrohep.2022.01.007

Wang D, Zou L, Luo J, et al. Potential diagnostic and prognostic value of the long non-coding RNA SNHG3 in human cancers: A systematic review and meta-analysis. Int J Biol Markers 2022;37:3-12. DOI: https://doi.org/10.1177/03936155221077121

Trifkovic B, Budak I, Vukelic D, et al. Analysis of accuracy and precision of optical 3D digitisation devices in dental computer-aided-design and computer-aided-manufacturing systems. Maejo Int J Sci Technol 2017;11:45-57.

Pētersone M, Ketners K, Krieviņš D, et al. Network for disease-specific networking strategy to increasing of public value: Latvia’s approach. In: Kantola JI, Nazir S, Salminen V, eds. Advances in Human Factors, Business Management and Leadership. Proceedings of the AHFE 2021 Virtual Conferences on Human Factors, Business Management and Society, and Human Factors in Management and Leadership, 2021 July 25-29, USA. Cham: Springer, 2021. pp. 363-70. DOI: https://doi.org/10.1007/978-3-030-80876-1_46

Cervena K, Vodicka P, Vymetalkova V. Diagnostic and prognostic impact of cell-free DNA in human cancers: Systematic review. Mutat Res Rev Mutat Res 2019;781:100-29. DOI: https://doi.org/10.1016/j.mrrev.2019.05.002

Toden S, Goel A. Non-coding RNAs as liquid biopsy biomarkers in cancer. Br J Cancer 2022;126:351-60. DOI: https://doi.org/10.1038/s41416-021-01672-8

Sundquist K, Sundquist J, Hedelius A, Memon AA. Diagnostic potential of circulating cell-free nuclear and mitochondrial DNA for several cancer types and nonmalignant diseases: A study on suspected cancer patients. Mol Carcinog 2020;59:1362-70. DOI: https://doi.org/10.1002/mc.23261

Park HJ, Lee SH, Chang, YS. Recent advances in diagnostic technologies in lung cancer. Korean J Intern Med 2020;35:257-68. DOI: https://doi.org/10.3904/kjim.2020.030

Shende P, Augustine S, Prabhakar B, Gaud RS. Advanced multimodal diagnostic approaches for detection of lung cancer. Expert Rev Mol Diagn 2019;19:409-17. DOI: https://doi.org/10.1080/14737159.2019.1607299

Nebgen DR, Lu KH, Bast Jr RC. Novel approaches to ovarian cancer screening. Curr Oncol Rep 2019;21:75. DOI: https://doi.org/10.1007/s11912-019-0816-0

Lepka P, Jedryka M, Misiek M, Matkowski R. Hysterectomy in Poland between 2011 and 2016. Changing trends in the surgical approach to hysterectomy. Ginekol Pol 2018;89:529-35. DOI: https://doi.org/10.5603/GP.a2018.0090

Budny A, Starosławska E, Budny B, et al. Epidemiology and diagnosis of breast cancer. Pol Med Mercurius 2019;46:195-204.

Basta A, Bidzinski M, Bienkiewicz A, et al. Recommendation of the Polish Society of Oncological Gynaecology on the diagnosis and treatment of epithelial ovarian cancer. Oncol Clin Pract 2015;11:233-43.

Svyatova G, Berezina G, Urazbayeva G, Murtazaliyeva A. Frequencies of diagnostically significant polymorphisms of hereditary breast cancer forms in BRCA1 and BRCA2 genes in the Kazakh population. Asian Pac J Cancer Prev 2023;24:3899-907. DOI: https://doi.org/10.31557/APJCP.2023.24.11.3899

Connal S, Cameron JM, Sala A, et al. Liquid biopsies: The future of cancer early detection. J Transl Med 2023;21:118. DOI: https://doi.org/10.1186/s12967-023-03960-8

Xu M, Ergin I, Beyaz S. Advances in diagnostic procedures and their applications in the era of cancer immunotherapy. Adv Exp Med Biol 2020;1244:37-50. DOI: https://doi.org/10.1007/978-3-030-41008-7_2

van der Strate I, Kazemzadeh F, Nagtegaal ID, et al. International consensus on the initial diagnostic workup of cancer of unknown primary. Crit Rev Oncol Hematol 2023;181:103868. DOI: https://doi.org/10.1016/j.critrevonc.2022.103868

Nasir A, Khan A, Li J, et al. Nanotechnology, a tool for diagnostics and treatment of cancer. Curr Top Med Chem 2021;21:1360-76. DOI: https://doi.org/10.2174/1568026621666210701144124

Pandey I, Misra V, Pandey AT, et al. Artificial intelligence technologies empowering identification of novel diagnostic molecular markers in gastric cancer. Indian J Pathol Microbiol 2021;64:S63-8. DOI: https://doi.org/10.4103/IJPM.IJPM_950_20

Bradshaw RA, Hondermarck H, Rodriguez H. Cancer proteomics and the elusive diagnostic biomarkers. Proteomics 2019;19:e1800445. DOI: https://doi.org/10.1002/pmic.201800445

Liu X, Jiang H, Wang X. Advances in cancer research: Current and future diagnostic and therapeutic strategies. Biosensors 2024;14:100. DOI: https://doi.org/10.3390/bios14020100

Brito B, Price TW, Gallo J, et al. Smart magnetic resonance imaging-based theranostics for cancer. Theranostics 2021;11:8706-37. DOI: https://doi.org/10.7150/thno.57004

Gaya A, Crook T, Plowman N, et al. Evaluation of circulating tumor cell clusters for pan-cancer noninvasive diagnostic triaging. Cancer Cytopathol 2021;129:226-38. DOI: https://doi.org/10.1002/cncy.22366

Wiley C, Wise CF, Breen M. Novel noninvasive diagnostics. Vet Clin North Am Small Anim Pract 2019;49:781-91. DOI: https://doi.org/10.1016/j.cvsm.2019.05.002

Gharehzadehshirazi A, Zarejousheghani M, Falahi S, et al. Biomarkers and corresponding biosensors for childhood cancer diagnostics. Sensors 2023;23:1482. DOI: https://doi.org/10.3390/s23031482

Latka K, Kolodziej W, Pawlak K, et al. Fully endoscopic spine separation surgery in metastatic disease – Case series, technical notes, and preliminary findings. Medicina (Kaunas) 2023;59:993. DOI: https://doi.org/10.3390/medicina59050993

Postic SD. X-ray diffraction technique in the analysis of phases of hydroxylapatite and calcium phosphate in a human jaw. Int J Biomed 2014;4:109-13.

Slivkina N, Abduldayeva A, Tardjibayeva S, et al. The health of the population, according to prenosological diagnostics. Georgian Med News 2020;303:188-93.

Jin C, Wang K, Oppong-Gyebi A, Hu J. Application of nanotechnology in cancer diagnosis and therapy – A mini-review. Int J Med Sci 2020;17:2964-73. DOI: https://doi.org/10.7150/ijms.49801

Gupta D, Roy P, Sharma R, et al. Recent nanotheranostic approaches in cancer research. Clin Exp Med 2024;24:8. DOI: https://doi.org/10.1007/s10238-023-01262-3

Bhushan S, Mittal A, Beg MF, Agarwal A. Missed gall bladder malignancy: A result of ignoring predisposing factors. Int J Med Med Res 2023;9:6-14. DOI: https://doi.org/10.61751/ijmmr/2.2023.06

Parker J. Uncovering cancer’s secrets: Could liquid biopsies and artificial intelligence hold the answers? Future Oncol 2023;19:1231-3. DOI: https://doi.org/10.2217/fon-2023-0428

Thakur T, Batra I, Luthra M, et al. Gene expression-assisted cancer prediction techniques. J Healthc Eng 2021;2021:4242646. DOI: https://doi.org/10.1155/2021/4242646

Ji X, Cui Q. Ancient genes can be served as pan-cancer diagnostic and prognostic biomarkers. J Cell Mol Med 2020;24:6908-15. DOI: https://doi.org/10.1111/jcmm.15347

Bahrami A, Ferns GA. Diagnostic, prognostic, and therapeutic value of miR-148b in human cancers. Curr Mol Med 2022;22:860-9. DOI: https://doi.org/10.2174/1566524021666211213123315

Palaz F, Kalkan AK, Can Z, et al. CRISPR-Cas13 system as a promising and versatile tool for cancer diagnosis, therapy, and research. ACS Synth Biol 2021;10:1245-67. DOI: https://doi.org/10.1021/acssynbio.1c00107

Rai A, Noor S, Ahmad SI, et al. Recent advances and implication of bioengineered nanomaterials in cancer theranostics. Medicine 2021;57:91. DOI: https://doi.org/10.3390/medicina57020091

Animesh S, Singh YD. A comprehensive study on aptasensors for cancer diagnosis. Curr Pharm Biotechnol 2021;22:1069-84. DOI: https://doi.org/10.2174/1389201021999200918152721

Landegren U, Hammond M. Cancer diagnostics based on plasma protein biomarkers: Hard times but great expectations. Mol Oncol 2021;15:1715-26. DOI: https://doi.org/10.1002/1878-0261.12809

Makler A, Asghar W. Exosomal biomarkers for cancer diagnosis and patient monitoring. Expert Rev Mol Diagn 2020;20:387-400. DOI: https://doi.org/10.1080/14737159.2020.1731308

Yadav S, Vadivelu R, Ahmed M, et al. Stretching cells – An approach for early cancer diagnosis. Exp Cell Res 2019;378:191-7. DOI: https://doi.org/10.1016/j.yexcr.2019.01.029

Polatova DSh, Madaminov AYu, Savkin AV, et al. PD-L1 and p53 expression in squamous cell carcinoma of the oropharynx depending on human papilloma virus status. Head Neck Tumors 2023;13:44-56. DOI: https://doi.org/10.17650/2222-1468-2023-13-2-44-56

Pal M, Muinao T, Boruah HPD, Mahindroo N. Current advances in prognostic and diagnostic biomarkers for solid cancers: Detection techniques and future challenges. Biomed Pharmacother 2022;146:112488. DOI: https://doi.org/10.1016/j.biopha.2021.112488

Wang XQ, Goytain A, Dickson BC, Nielsen TO. Advances in sarcoma molecular diagnostics. Genes Chromosomes Cancer 2022;6:332-45. DOI: https://doi.org/10.1002/gcc.23025

Kim DH, Kim Y, Kim SW, Hwang SH. Use of narrowband imaging for the diagnosis and screening of laryngeal cancer: A systematic review and meta-analysis. Head Neck 2020;42:2635-43. DOI: https://doi.org/10.1002/hed.26186

Mueller CG, Gaiddon C, Venkatasamy A. Current clinical and pre-clinical imaging approaches to study the cancer-associated immune system. Front Immunol 2021;12:716860. DOI: https://doi.org/10.3389/fimmu.2021.716860

Wong PK, Chan IN, Yan HM, et al. Deep learning based radiomics for gastrointestinal cancer diagnosis and treatment: A minireview. World J Gastroenterol 2022;28:6363-79. DOI: https://doi.org/10.3748/wjg.v28.i45.6363

Lavasanifar A, Sharp CN, Korte EA, et al. Long interspersed nuclear element-1 mobilization as a target in cancer diagnostics, prognostics and therapeutics. Clin Chim Acta. Int J Clin Chem 2019;493:52-62. DOI: https://doi.org/10.1016/j.cca.2019.02.015

Ivashko M, Burmei S, Yusko L, et al. Microbiological diagnostics: From traditional to molecular genetic methods: A literature review. Bull Med Biol Res 2023;5:34-41. DOI: https://doi.org/10.61751/bmbr/4.2023.34

How to Cite



Innovations in cancer diagnosis and treatment: prospects and challenges. (2024). Healthcare in Low-Resource Settings, 12(s2). https://doi.org/10.4081/hls.2024.12831