https://doi.org/10.4081/ecj.2026.15676
Response to: Potential and limitations of large language models in acute chest pain triage
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Published: 10 July 2026
Dear Editor-in-Chief,
We would like to thank Shinde and colleagues for their thoughtful comments on our article, “Evaluating the predictive accuracy of ChatGPT in risk stratification for chest pain in the emergency department”.1,2 We are grateful for their appreciation of both the rationale of the study and the dynamic methodology adopted, in which ChatGPT was evaluated across sequential phases of the emergency department assessment.2 [...]
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1) Malalan F, Zaboli A, Fiore A, et al. Evaluating the predictive accuracy of ChatGPT in risk
stratification for chest pain in the emergency department. Emerg Care J 2025;21:13829 DOI: https://doi.org/10.4081/ecj.2025.13829
2) Shinde V, Kanani P, Bhimani K. Potential and limitations of large language models in acute chest pain triage. Response to Evaluating the predictive accuracy of ChatGPT in risk stratification for chest pain in the emergency department. Emerg Care J 2026;22:15130. DOI: https://doi.org/10.4081/ecj.2026.15130
3) Günay S, Öztürk A, Özerol H, Yiğit Y. Comparison of emergency medicine specialist, cardiologist, and ChatGPT in electrocardiography assessment. Am J Emerg Med 2024;80:51-60. DOI: https://doi.org/10.1016/j.ajem.2024.03.017
4) Günay S, Öztürk A, Yiğit Y. The accuracy of Gemini, GPT-4, and GPT-4o in ECG analysis: a comparison with cardiologists and emergency medicine specialists. Am J Emerg Med. 2024;84:68-73. DOI: https://doi.org/10.1016/j.ajem.2024.07.043
5) Rjoob K, Bond R, Finlay D, et al. Machine learning and the electrocardiogram over two decades: Time series and meta-analysis of the algorithms, evaluation metrics and applications. Artif Intell Med 2022;132:102381. DOI: https://doi.org/10.1016/j.artmed.2022.102381
CRediT authorship contribution
Arian Zaboli, conceptualization; writing - review & editing; writing - original draft; Gianni Turcato, writing - review & editing; writing - original draft.
Supporting Agencies
Data Availability Statement
Data available on request due to privacy/ethical restrictions.
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