Anomalous drainage of left renal vein into the azygos venous system without inferior vena cava interruption: a novel anatomic variant

Authors

  • Joe Khoury Department of Interventional Radiology, Emory University School of Medicine, Atlanta https://orcid.org/0009-0009-3494-4492
  • Kadir Ozler Department of Interventional Radiology, Hofstra University Zucker School of Medicine, Hempstead https://orcid.org/0000-0002-0201-1905
  • Ahmad Alkadri Department of Interventional Radiology, Moffitt Cancer Center, University of South Florida Morsani College of Medicine, Tampa https://orcid.org/0009-0008-6625-216X
  • Brendan Ryu Transitional Year Program, South Shore University Hospital, Northwell Health, New York
  • Mustafa Al-Roubaie Department of Interventional Radiology, Moffitt Cancer Center, University of South Florida Morsani College of Medicine, Tampa https://orcid.org/0000-0002-1054-2642

DOI:

https://doi.org/10.4081/vl.2025.13842

Keywords:

Anomalous venous drainage, left renal vein, azygos vein, vascular anomaly

Abstract

Anomalies of the Left Renal Vein (LRV) are often asymptomatic and found incidentally, but can have major ramifications on both surgical and interventional procedures. We present the case of a 63-year-old male who was incidentally found to have a novel venous anatomic variant, not previously described in the literature. His LRV drains into the azygos venous system up into the chest via the hemiazygos vein, despite the presence of a normal, patent and uninterrupted right-sided Inferior Vena Cava (IVC), and with no communication to the IVC. This configuration differs from known variants that lead to azygous venous drainage such as posterior nutcracker syndrome of a retroaortic left renal vein or azygos continuation of the IVC with congenital interruption. Venous anomalies involving the LRV, including in this patient, may increase the risk of bleeding during retroperitoneal surgery or complicate endovascular procedures involving the left renal, adrenal or gonadal veins. Recognition of variant venous anatomy is key for pre-procedural planning to avoid unnecessary complications.

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Published

04-06-2025

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Section

Case Reports

How to Cite

Anomalous drainage of left renal vein into the azygos venous system without inferior vena cava interruption: a novel anatomic variant . (2025). Veins and Lymphatics, 14. https://doi.org/10.4081/vl.2025.13842