160 | Short-term mild caloric restriction induces early adaptive metabolic and mitochondrial responses in the liver of healthy rats: Martina Coletta1, Vincenzo Migliaccio1, Giuliana Panico2, Ilaria Di Gregorio1, Assunta Lombardi2, Lillà Lionetti1 | 1Dept Chemistry and Biology "A Zambelli", University of Salerno, Italy; 2Dept Biology, University of Naples Federico II, Naples, Italy. J Biol Res. 2026;99(s1). doi:10.4081/jbr.2026.15412