060 | Interdomain interactions and pH modulate folding intermediates in MAGI1 PDZ4: Cosmin Marian Obreja1, Valeria Pennacchietti2, Dimitrios Marinidis1, Sara Di Matteo3, Rodolfo Ippoliti1, Stefano Gianni2, Francesca Malagrinò1 | 1University of L’Aquila, Italy; 2University “La Sapienza” of Rome, Italy; 3University of Chieti-Pescara, Italy. J Biol Res. 2026;99(s1). doi:10.4081/jbr.2026.15312