009 | Metabolic adaptation to hypoxia via lipid droplet accumulation in a 3D hepatocellular carcinoma model: Giorgia Cannatà1, Caterina Faggio1|2, Maria Giovanna Rizzo1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2Department of Eco-sustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Naples, Italy. J Biol Res. 2026;99(s1). doi:10.4081/jbr.2026.15261