147 | Screening of Novel Metabotropic Glutamate Receptor 4-Oriented Molecules in an in Vitro Model of Parkinson’s Disease: Cristina Giuffré1, Miriana Scordino1, Giulia Urone1, Miriam Buttacavoli1, Alessandra Montalbano2, Marilia Barreca2, Roberta Bivacqua2, Paola Barraja2, Virginia Spano’2, Giuseppa Mudo’1, Valentina Di Liberto1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostic, University of Palermo, Palermo, Italy; 2Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Palermo, Italy. J Biol Res 2026, 99 (s1). https://doi.org/10.4081/jbr.2026.15399.