069 | Comparative Analysis of Inflammatory and Redox Responses in Human and Rat Macrophages Exposed to Calcium-Doped Mesoporous Silica Nanoparticles: Styliani Axypolitou1, Antonietta Ligas2, Ioannis Tsamesidis1, Georgia K. Pouroutzidou1, Pier Luigi Fiori2, Antonella Pantaleo2, Eleana Kontonasaki1 | 1Department of Prosthodontics, School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece 2Department of Biomedical Sciences, Division of Microbiology and Virology, University of Sassari, Italy. J Biol Res 2026, 99 (s1). https://doi.org/10.4081/jbr.2026.15321.