Technique for intraoperatory harvesting of adipose derived stem cells: towards cell treatment of recalcitrant ulcers

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Ilaria Zollino *
Maria Grazia Sibilla
Sergio Gianesini
Erica Menegatti
Mirko Tessari
Anna Maria Malagoni
(*) Corresponding Author:
Ilaria Zollino | zlllri@unife.it

Abstract

Successful wound and ulcer repair remains a major biomedical challenge in the 21st Century. Innovative and alternative treatment options have been investigated over the last decade and stem cells application has been suggested as a possible novel therapy for regenerative medicine. In particular, stem cells derived from adipose tissue have been attracting a lot of attention in recent years as an alternative to the use of cells derived from bone marrow. This technical note describes the procedure introduced by Coleman for intraoperatory harvesting of adipose derived-stem-cells and proposes a rationale for using it in difficult wound healing and recalcitrant ulcers.

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Author Biographies

Ilaria Zollino, Department of Morphology, Surgery and Experimental Medicine, Section of Translational of Medicine and Surgery, University of Ferrara

Department of Morphology, Surgery and Experimental Medicine, Section of Translational of Medicine and Surgery, University of Ferrara, Italy

Maria Grazia Sibilla, Sant’Anna University Hospital, Unit of Translational Surgery and Vascular Diseases Center, Ferrara

Sant’Anna University Hospital, Unit of Translational Surgery and Vascular Diseases Center, Ferrara, Italy

Sergio Gianesini, Department of Morphology, Surgery and Experimental Medicine, Section of Translational of Medicine and Surgery, University of Ferrara; Sant’Anna University Hospital, Unit of Translational Surgery and Vascular Diseases Center, Ferrara

Department of Morphology, Surgery and Experimental Medicine, Section of Translational of Medicine and Surgery, University of Ferrara, Italy

Sant’Anna University Hospital, Unit of Translational Surgery and Vascular Diseases Center, Ferrara, Italy

Erica Menegatti, Department of Morphology, Surgery and Experimental Medicine, Section of Translational of Medicine and Surgery, University of Ferrara; Sant’Anna University Hospital, Unit of Translational Surgery and Vascular Diseases Center, Ferrara

Department of Morphology, Surgery and Experimental Medicine, Section of Translational of Medicine and Surgery, University of Ferrara, Italy

Sant’Anna University Hospital, Unit of Translational Surgery and Vascular Diseases Center, Ferrara, Italy

Mirko Tessari, Department of Morphology, Surgery and Experimental Medicine, Section of Translational of Medicine and Surgery, University of Ferrara; Sant’Anna University Hospital, Unit of Translational Surgery and Vascular Diseases Center, Ferrara

Department of Morphology, Surgery and Experimental Medicine, Section of Translational of Medicine and Surgery, University of Ferrara, Italy

Sant’Anna University Hospital, Unit of Translational Surgery and Vascular Diseases Center, Ferrara, Italy

Anna Maria Malagoni, Sant’Anna University Hospital, Unit of Translational Surgery and Vascular Diseases Center, Ferrara

Sant’Anna University Hospital, Unit of Translational Surgery and Vascular Diseases Center, Ferrara, Italy