γA gene repeats polymorphism for the analysis of haplotypes of abnormal hemoglobins
AbstractAim of this study was to analyze γ A gene repeat polymorphism for the analysis of haplotypes of hemoglobin (Hb) variants such as Hb S, Hb D-Punjab, Hb O-Arab. Sickle cell cases had mainly Benin and Arab/Indian haplotype. We found three different haplotypes among Hb S, Hb O Arab and Hb D-Punjab cases. We named these three variants as Anatolian-1 and Anatolian-2 and Asian. Our data revealed that Hb O Arab may arise twice one from Asia and the other from Europe.
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Copyright (c) 2014 Nejat Akar, Kadir Sipahi, Ece Akar, Erkan Yilmaz
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