Coagulation and thrombotic risk in thalassemia intermedia

  • A.T. Taher | paola.granata@pagepress.org Department of Internal Medicine, Hematology-Oncology Division, American University of Beirut Medical Centre, Beirut, Lebanon.
  • K.M. Musallam Department of Internal Medicine, Hematology-Oncology Division, American University of Beirut Medical Centre, Beirut, Lebanon.

Abstract

As the life expectancy of β-thalassemia patients has markedly improved over the last few decades, several manifestations are increasingly recognized. The presence of a high incidence of thromboembolic events, mainly in thalassemia intermedia patients, has led to the identification of a hypercoagulable state in thalassemia. In this review, the current clinical experience attributed to the coagulopathy in thalassemia intermedia patients is summarized. Recommendations for thrombosis prophylaxis are also discussed.

 

近几十年来,随着β地中海贫血患者的平均寿命得到显著提高,几种试验结果得到了进一步证实。 地中海贫血中间患者出现高发血栓栓塞症,得以识别地中海贫血高凝状态。 本文总结了当前地中海贫血中间患者的凝血病临床经验, 也讨论了血栓症预防的推荐方法。

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Published
2011-12-30
Keywords:
thalassemia intermedia, hypercoagulability, thromboembolism, stroke, splenectomy, transfusion.
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How to Cite
Taher, A., & Musallam, K. (2011). Coagulation and thrombotic risk in thalassemia intermedia. Thalassemia Reports, 1(1), e15. https://doi.org/10.4081/thal.2011.s2.e15