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The present paper describes the role of ozone in the treatment of the acute phase of ischemic heart disease. Two studies are presented: the first mechanically induced myocardial ischemia in rats; the second involved 42 consecutive patients with an outcome comparable to the UA/non-Q wave NSTEMI AMI group of the ENACT study, divided randomly into 2 groups with homogeneous quantitative levels (NYHA class II-III) and was evaluated at weeks 8 and 12 of treatment with ozone. Both studies confirm that i) the effectiveness of ozone therapy increases in relation to how early and how long treatment is performed; and ii) that ozone reduces the relative risk both of ischemic (infarct extension) and arrhythmia complications.
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