Shigella flexneri-induced vaginitis in a prepubertal children: description of a case

  • Antonella Restelli |
  • Manuela Colosimo
  • Anna Maraschini
  • Anna Grancini
  • Rosaria Colombo
  • Romualdo Grande
  • Maria Rosa Araldi
  • Erminio Torresani


In prepuberal girls vulvo-vaginitis are caused by germs of intestinal origin,mycetes, Gardnerella vaginalis, protozoa. Shigella is an uncommon agent able to induce valvovaginitis in children. We report the case of a 7-year-old girl with chronic vulvo-vaginitis caused by S. flexneri. Antibiotic Susceptibility Testing revealed that S. flexnery was sensible to cefotaxime, amoxicillin, imipenem, ciprofloxacin, but resistant to amikacin, cefazolin, gentamycin, ampicillin and tetracycline. A treatment with ciprofloxacin brought to a rapid resolution of all symptoms. At the follows up at 3 and 6 months the patient did not report symptoms of infection or articular cartilage abnormality; microbiological evaluations were also negative. Even if it is a single case report and other clinical trial may be performed in order to validate this hypothesis,we speculate that in patient with vulvo-vaginal infection living in environment with low hygiene care, a carefully microbiological evaluation of uncommon agents may be performed.



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Original Articles
Vaginitis, Shigella, S. flexneri, Prepubertal age
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How to Cite
Restelli, A., Colosimo, M., Maraschini, A., Grancini, A., Colombo, R., Grande, R., Araldi, M. R., & Torresani, E. (2011). Shigella flexneri-induced vaginitis in a prepubertal children: description of a case. Microbiologia Medica, 26(2).

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