Antimicrobial susceptibility of enterococci from Italian patients with infective endocarditis

  • Claudio Farina | farina.claudio@sancarlo.mi.it
  • Giuseppe Russello
  • Annibale Raglio
  • Francesca Vailati
  • Veronica Ravasio
  • Maria Bruna Pasticci
  • Pierangelo Chinello
  • Claudio Scarparo
  • Gruppo SEI

Abstract

The epidemiological and clinical study “Studio Endocarditi Italiane” (SEI) evaluated 947 cases of infective endocarditis in 2004-2008. Enterococcal aethiology was described in 11% cases.The aim of our study was to evacuate the in vitro activity of twelve antibiotics alone and in association against 20 strains (15 E. faecalis, 5 E. faecium). Results show the in vitro activity of tigecyicline, daptomicine and linezolid. Synergism is appreciated for ceftriaxone-fosfomycin (FICindex50=0.34, FICindex90=0.56) against E. faecalis and for imipenem-fosfomycin against E. faecium.The majority of the tested strains show addition using ampicillin-ceftriaxone (FICindex50=0.85, FICindex90=1.01) and moxifloxacin- tigecycline (FICindex50=0.77, FICindex90=1.96).

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Published
2010-03-31
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Original Articles
Keywords:
Antimicrobial associations, Antimicrobial susceptibility, Enterococcus, Infective endocarditis
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How to Cite
Farina, C., Russello, G., Raglio, A., Vailati, F., Ravasio, V., Pasticci, M., Chinello, P., Scarparo, C., & SEI, G. (2010). Antimicrobial susceptibility of enterococci from Italian patients with infective endocarditis. Microbiologia Medica, 25(1). https://doi.org/10.4081/mm.2010.2479

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