Antimicrobial susceptibility of enterococci from Italian patients with infective endocarditis
AbstractThe epidemiological and clinical study “Studio Endocarditi Italiane” (SEI) evaluated 947 cases of infective endocarditis in 2004-2008. Enterococcal aethiology was described in 11% cases.The aim of our study was to evacuate the in vitro activity of twelve antibiotics alone and in association against 20 strains (15 E. faecalis, 5 E. faecium). Results show the in vitro activity of tigecyicline, daptomicine and linezolid. Synergism is appreciated for ceftriaxone-fosfomycin (FICindex50=0.34, FICindex90=0.56) against E. faecalis and for imipenem-fosfomycin against E. faecium.The majority of the tested strains show addition using ampicillin-ceftriaxone (FICindex50=0.85, FICindex90=1.01) and moxifloxacin- tigecycline (FICindex50=0.77, FICindex90=1.96).
- Abstract views: 852
- PDF: 1222
Copyright (c) 2010 Claudio Farina, Giuseppe Russello, Annibale Raglio, Francesca Vailati, Veronica Ravasio, Maria Bruna Pasticci, Pierangelo Chinello, Claudio Scarparo, Gruppo SEI
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.