HIV 1-2 Ag/Ab selective and combined detection by a new rapid point-of-care test

Marta Monari; Serenella Valaperta; Eleonora Baldassarre; Roberto Assandri; Alessandro Montanelli

doi:10.4081/mm.2010.2412

HIV 1-2 Ag/Ab selective and combined detection by a new rapid point-of-care test

https://doi.org/10.4081/mm.2010.2412

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Vol. 25 No. 4 (2010)

Submitted: 14 February 2014
Accepted: 14 February 2014

Published: 31 December 2010

HIV, exposure, POCT

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Authors

In order to reduce the window phase between time of human immunodeficiency virus (HIV) exposure and source’s results of laboratory investigations, we evaluated the analytical performance of a new point of care test for simultaneous detection of HIV Abs and HIV Ag.We tested 48 serum samples by HIV Combo Ag/Ab Abbott Diagnostic®, USA; by Western Blot Matrix HIV 1/2 Abbott®, USA and by the new POCT test HIV 1/2 Ag/Ab Combo Inverness Medical®, UK. Good concordance of results was recordered with analytical performance (sensitivity and specificity) and diagnostic accuracy of 100%.Thus this new test is ideal for rapid laboratory investigation when the time for appropriate prophylactic therapy is very important, such as found in exposure in the workplace.

Monari, M., Valaperta, S., Baldassarre, E., Assandri, R., & Montanelli, A. (2010). HIV 1-2 Ag/Ab selective and combined detection by a new rapid point-of-care test. Microbiologia Medica, 25(4). https://doi.org/10.4081/mm.2010.2412