Comparison of three assays currently used for diagnosis of legionellosis

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Maria Chiucini *
Anna Fabio
Marisa Meacci
Barbara Meccugni
Valentina Gilioli
Valeria Petocchi
Giuliana Fabio
Anna Maria Teresa Sabbatini
Sara Tagliazucchi
Sandra Mattioli
Fabio Rumpianesi
(*) Corresponding Author:
Maria Chiucini | chiucini@yahoo.it

Abstract

The laboratory diagnosis of Legionnaires’ disease is extremely complex due to the difficulty of isolating and identifying the etiological agent in a short time and also for the frequent late appearance of antibodies. For this reason it should use not only the cultures but also other diagnostic tests such as urinary antigen and antibody research. Our study evaluated the performance of these methods.We calculated the positive predictive value (PPV) and negative predictive value (NPV), sensitivity and specificity of each test.

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