Valutazione comparativa di un test immunocromatografico “Helicobacter pylori Antigen Onestep Test” e di due test immunoenzimatici “Fecal-clean H. pylori Ag” e “Amplified IDEIATM Hp StARTM” per la diagnosi di infezione da Helicobacter pylori attraverso ric

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Antonella Marangoni *
Alessandra Moroni
Francesca Cavrini
Elisa Storni
Manuela Donati
Vittorio Sambri
(*) Corresponding Author:
Antonella Marangoni | marangoni@orsola-malpighi.med.unibo.it

Abstract

Helicobacter pylori causes gastritis and peptic ulcer disease and has been associated with gastric malignancies. During recent years, non invasive diagnostic tests have gained in significance.Well-established non invasive tests are serology and the [13C] urea breath test. Serology, however, is not suitable for an early follow-up examination due to the slow reduction of the anti-H. pylori antibody titer after successful treatment. The [13C] urea breath test-delivering accurate results both in the pretreatment examination of infected individuals and in the early post treatment control-fulfills the demands for such a test. However, expensive instrumentation and a specialized technician are required. Since infected individuals excrete H. pylori in stool specimens, a sufficiently accurate test using feces would be an important alternative to [13C] urea breath test. In this study we compared the diagnostic performances of the immunocromatographic test “Helicobacter pylori Antigen Onestep Test” with those of two enzyme linked immunoassay tecniques “Fecal-clean H. pylori Ag” and “Amplified IDEIATM Hp StARTM” for detection of H. pylori antigens in stool specimens.The values of agreement ranged from 89.6% to 93.6%.

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