TY - JOUR AU - Mandolfino, F. AU - Frascio, M. AU - Perotti, S. AU - Lazzara, F. AU - Imperatore, M. AU - Bruno, S. PY - 2013/01/30 Y2 - 2024/03/29 TI - Diabetes mellitus and upper gut motility JF - Journal of Biological Research - Bollettino della Società Italiana di Biologia Sperimentale JA - J Biol Res VL - 86 IS - 1 SE - Original Articles DO - 10.4081/jbr.2013.3670 UR - https://www.pagepressjournals.org/jbr/article/view/3670 SP - AB - The aim of the study is to detect the presence of esophageal motor disorders in type I and II diabetic patients, and to establish whether there is any difference between patients with and without neuropathy. 118 diabetics patients (34 type I and 84 type II) were investigated by water-perfused stationary esophageal manometry. Data were correlated with the presence of peripheral neurophaty. As a result 71% of patients affected by peripheral neuropathy showed manometric abnormalities against the 37% of the patients without neuropathy. Our experience has shown that patients with diabetes mellitus frequently present esophageal symptoms and manometric abnormalities. Manometric study of the esophagus has to be considered a useful investigative tool to manage and monitorize the gastrointestinal abnormalities in patients affected by diabetes mellitus. ER -