In vitro Assessment of Anti-Inflammatory and COX-2 inhibitory action of some medicinal plants

Submitted: December 1, 2019
Accepted: May 25, 2020
Published: August 3, 2020
Abstract Views: 1462
PDF: 696
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Objective of this research was to evaluate the anti-inflammatory and COX-2 inhibitory properties of celery, myrrh, aqueous and alcoholic fenugreek plant extracts. The Human Red Blood Cell membrane stabilization (HRBC) method was used to evaluate the anti-inflammatory effect and the Enzyme Immunoassay (EIA) was used to evaluate the COX-2 inhibitory actions. The celery extract showed excellent anti-inflammatory and COX-2 inhibition potency. The other extracts (myrrh and fenugreek) showed less activity that might indicate high efficacy of celery. This may be attributed to the plant constituents, mainly to a compound known as 3-n-butylphthalide, which is the most powerful of all healing factors of celery.

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Ramadhan, U. (2020). In vitro Assessment of Anti-Inflammatory and COX-2 inhibitory action of some medicinal plants. Journal of Biological Research - Bollettino Della Società Italiana Di Biologia Sperimentale, 93(1). https://doi.org/10.4081/jbr.2020.8723