Relationship between magnetism and prion protein

https://doi.org/10.4081/jbr.2010.4434

Abstract

The mechanism of conversion of the normal prion protein (PrPC) into aggregates of its pathological conformer (PrPSc) reamins unclear. The aim of this study was to evaluate the effects induced by exposure of biological samples containing PrPSC to a magnetic field induced prominent molecular changes of samples indicated by the IR spectra located in the region that contains contribution primarily from absorption of amides. This finding suggests the existence of a strong correlation between magnetism and PrPsc and supports a new hypothesis that explains the conversion of normal PrPc to abnormal isoform PrPsc.
Crossref
Scopus
Google Scholar
Europe PMC

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.
Published
2010-01-30
Info
Issue
Vol. 83 No. 1 (2010)
Section
Original Articles
Keywords:
prion protein, magnetism, IR spectra
Statistics
  • Abstract views: 537

  • PDF: 376
How to Cite
Balzano, F., Zedda, M., Basagni, M., Dei Giudici, S., Danani, A., & Sanna, V. (2010). Relationship between magnetism and prion protein. Journal of Biological Research - Bollettino Della Società Italiana Di Biologia Sperimentale, 83(1). https://doi.org/10.4081/jbr.2010.4434

Copyright (c) 2010 F. Balzano, M. Zedda, M. Basagni, S. Dei Giudici, A. Danani, V. Sanna

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.