Diabetes mellitus and upper gut motility

  • F. Mandolfino | succlavia@yahoo.it
  • M. Frascio
  • S. Perotti
  • F. Lazzara
  • M. Imperatore
  • S. Bruno

Abstract

The aim of the study is to detect the presence of esophageal motor disorders in type I and II diabetic patients, and to establish whether there is any difference between patients with and without neuropathy. 118 diabetics patients (34 type I and 84 type II) were investigated by water-perfused stationary esophageal manometry. Data were correlated with the presence of peripheral neurophaty. As a result 71% of patients affected by peripheral neuropathy showed manometric abnormalities against the 37% of the patients without neuropathy. Our experience has shown that patients with diabetes mellitus frequently present esophageal symptoms and manometric abnormalities. Manometric study of the esophagus has to be considered a useful investigative tool to manage and monitorize the gastrointestinal abnormalities in patients affected by diabetes mellitus.

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Published
2013-01-30
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Original Articles
Keywords:
neuropathy, diabetes mellitus, esophagus, manometry, motility
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How to Cite
Mandolfino, F., Frascio, M., Perotti, S., Lazzara, F., Imperatore, M., & Bruno, S. (2013). Diabetes mellitus and upper gut motility. Journal of Biological Research - Bollettino Della Società Italiana Di Biologia Sperimentale, 86(1). https://doi.org/10.4081/jbr.2013.3670