ALTERATION OF GENE EXPRESSION IN LEUKOCYTES FROM RECOMBINANT SOMATOTROPIN TREATED ANIMALS: SEARCHING FOR INSPECTION INDICATORS


Submitted: 8 February 2013
Accepted: 8 February 2013
Published: 19 December 2008
Abstract Views: 685
PDF: 1076
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Authors

  • L Castigliego Dipartimento di Patologia Animale Profilassi ed Igiene degli Alimenti Università di Pisa, Italy.
  • A. Armani Dipartimento di Patologia Animale Profilassi ed Igiene degli Alimenti Università di Pisa, .
  • G Grifoni Istituto Zooprofilattico Sperimentale di Lazio e Toscana, Roma, Italy.
  • R. Rosati Istituto Zooprofilattico Sperimentale di Lazio e Toscana, Roma, .
  • M. Mazzi Istituto Sperimentale per la Zootecnia, Roma, Italy.
  • A. Guidi Dipartimento di Patologia Animale Profilassi ed Igiene degli Alimenti Università di Pisa, .
  • D. Gianfaldoni Dipartimento di Patologia Animale Profilassi ed Igiene degli Alimenti Università di Pisa, .
  • NR Brizioli Istituto Zooprofilattico Sperimentale di Lazio e Toscana, Roma, .
Besides immunochemical approaches, biomolecular studies can be carried out in order to discover a greater number of biological indicators to be exploited for the identification of bovines treated with recombinant somatotropin (rbST). With this aim, we analysed the expression of a number of genes related to the somatotropic axis in leucocytes from rbST treated cows and non-treated animals. Significant differences were observed in the genes IGF-1,IGFBP-1, IGFBP-4 and the I- 5’UTR variant of the GHR gene.

1.
Castigliego L, Armani A, Grifoni G, Rosati R, Mazzi M, Guidi A, Gianfaldoni D, Brizioli N. ALTERATION OF GENE EXPRESSION IN LEUKOCYTES FROM RECOMBINANT SOMATOTROPIN TREATED ANIMALS: SEARCHING FOR INSPECTION INDICATORS. Ital J Food Safety [Internet]. 2008 Dec. 19 [cited 2024 Mar. 28];1(2):29-31. Available from: https://www.pagepressjournals.org/ijfs/article/view/ijfs.2008.2.29

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