@article{Lai_Pelagatti_Pagnini_Baldini_Versari_Magazzini_2020, title={A rare case of acute alcohol intoxication mimicking an electrocardiographic pattern for acute coronary syndrome with ST-segment elevation}, volume={16}, url={https://www.pagepressjournals.org/ecj/article/view/8596}, DOI={10.4081/ecj.2020.8596}, abstractNote={<p>A patient presenting an ST-segment elevation could represent a life-threatening condition in Emergency Department (ED). This case shows how sometimes, a chronic, and more often, an acute abuse of alcohol is related to important harmful effects on myocardial contractility. The authors present a case of a 19-year-old male of oriental-Asiatic origin admitted unconscious to ED with alcoholic fetor: on electrocardiogram a significant and widespread STsegment elevation was observed. A bedside echocardiography showed no abnormalities in segmental kinetics; therefore electrocardiogram- alterations could be related to a coronary spasm. The literature is poor about this effect induced by acute alcohol ingestion: the pathophysiological mechanism at the base of the abnormal muscle contractility, seems to be related to an impairment in cyclic guanosine monophosphate production, although a second and less probable hypothesis could be an altered intracellular concentration of calcium levels.</p>}, number={1}, journal={Emergency Care Journal}, author={Lai, Franco and Pelagatti, Lorenzo and Pagnini, Chiara and Baldini, Alessio and Versari, Daniele and Magazzini, Simone}, year={2020}, month={Apr.} }