Frequency of polypharmacy and drug interactions in inpatients in the emergency department, Southwest of Iran

  • Mobina Tahmasebivand School of Pharmacy, Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Islamic Republic of.
  • Hassan Barzegari | h_b1979@yahoo.com Department of Emergency Medicine, Golestan General Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Islamic Republic of.
  • Mandana Izadpanah Department of Clinical Pharmacy, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Islamic Republic of.

Abstract

This study aimed to evaluate the polypharmacy extent and the frequency and severity of drug interactions by evaluating inpatients in the emergency department. In this epidemiologicaldescriptive study, data were collected retrospectively by reviewing medical records of 92 hospitalized patients in the emergency department with a stay over 48 hours. Out of the study population, 54.3% and 45.7% were respectively male and female, with a mean age of 59.09. In terms of hospitalization, 27.2% and 16.3% were hospitalized due to heart problems and trauma, respectively and the mean length of hospitalization was 3.91 with a standard deviation of 2.57 days. The mean drug received was 8.48, with a standard deviation of 4.48. Of the patients, 81.5% received more than 5 drugs; in addition, the observed amounts of drug interactions of A, B, C, D, and X were 2.5%, 17%, 59.3%, 19.5%, and 1.9%, respectively. The drug interaction prevalence in inpatients in the emergency department was high. The presence of a pharmacist is necessary to identify drug interactions and reduce drug-therapy problems to provide quality services.

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Published
2021-03-18
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Original Articles
Keywords:
Polypharmacy, drug interaction, emergency department
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How to Cite
Tahmasebivand, M., Barzegari, H., & Izadpanah, M. (2021). Frequency of polypharmacy and drug interactions in inpatients in the emergency department, Southwest of Iran. Emergency Care Journal, 17(1). https://doi.org/10.4081/ecj.2021.9082